biostudies-literatureAdamov DState Assignment from Russia's Ministry of Science and Higher EducationRussian Science Foundation1149https://www.ebi.ac.uk/biostudies/studies/S-EPMC12562464biostudies-literatureUnknown16(10)<b>Background/Objectives</b>: The eastern periphery of the Slavic expansion (the Volga-Oka region) is the most promising region for reconstructing interactions between Slavic and pre-Slavic populations of the East European Plain. Unlike most pre-Slavic tribes, its autochthonous population practiced inhumation instead of cremation, leaving us with some ancient DNA for analysis. <b>Methods</b>: The region's modern and ancient Y-chromosome gene pools are dominated by the haplogroup R1a: its frequency reaches 56% in Ryazan Russians (n = 302) and 44% in the Finnic peoples of Mordovia (n = 633). This encouraged us to analyze its Y-SNPs and Y-STRs. <b>Results</b>: Using 2 independent methods of phylogeny analysis, we identified 10 informative Y-STR clusters within R1a, dating back 1600-2900 YBP. GenesPre-Slavic and Slavic Interaction at Eastern Periphery of Slavic Expansion in Northeastern Europe (Y-Gene Pools of Volga-Oka Region).PMC1256246425-28-01594124060400040-3Chernyaeva LGorin IProkhortchouk EGoncharova NPonomarev GShlykov AAdamov DPotanina AVoronina MGavrilov AZhur KBalanovska ERusakov DKabaev DPocheshkhova EfalsePre-Slavic and Slavic Interaction at Eastern Periphery of Slavic Expansion in Northeastern Europe (Y-Gene Pools of Volga-Oka Region).<b>Background/Objectives</b>: The eastern periphery of the Slavic expansion (the Volga-Oka region) is the most promising region for reconstructing interactions between Slavic and pre-Slavic populations of the East European Plain. Unlike most pre-Slavic tribes, its autochthonous population practiced inhumation instead of cremation, leaving us with some ancient DNA for analysis. <b>Methods</b>: The region's modern and ancient Y-chromosome gene pools are dominated by the haplogroup R1a: its frequency reaches 56% in Ryazan Russians (n = 302) and 44% in the Finnic peoples of Mordovia (n = 633). This encouraged us to analyze its Y-SNPs and Y-STRs. <b>Results</b>: Using 2 independent methods of phylogeny analysis, we identified 10 informative Y-STR clusters within R1a, dating back 1600-2900 YBP. 2025-01-01T00:00:00Z2025 Sep2026-05-15T03:11:04.636Z2026-05-15T03:08:15.716ZS-EPMC125624644115336610.3390/genes16101149