biostudies-literatureUnknown13(10)Olguin-Montiel M<h4>Background</h4>Depression is one of the most common mental disorders among undergraduate students, particularly those in medical training, who face high academic demands and emotional burdens. Biological factors such as lipid abnormalities have been proposed as contributors to depressive symptoms, although evidence in this group is scarce. Therefore, we aimed to evaluate the association between triglyceride and total cholesterol levels and depressive symptoms in medical students.<h4>Methods</h4>We conducted a cross-sectional study including 219 medical students from a public university in Mexico. Depressive symptoms were assessed using the CESD-7 scale, validated in the Mexican population. Fasting triglyceride and total cholesterol concentrations were measured with the Accutrend Plus aDiseases (Basel, Switzerland)326https://www.ebi.ac.uk/biostudies/studies/S-EPMC12562626biostudies-literatureTriglycerides, Cholesterol, and Depressive Symptoms Among Undergraduate Medical Students: A Cross-Sectional Study.PMC12562626Mejia-Blanquel MACastaneda-Marquez ACCano-Estrada EAOlguin-Montiel MRazo-Blanco-Hernandez DMHernandez-Mariano JAOlmos-Rivera GMCureno-Diaz MAFernandez-Sanchez VAlvarez-Flores AfalseTriglycerides, Cholesterol, and Depressive Symptoms Among Undergraduate Medical Students: A Cross-Sectional Study.<h4>Background</h4>Depression is one of the most common mental disorders among undergraduate students, particularly those in medical training, who face high academic demands and emotional burdens. Biological factors such as lipid abnormalities have been proposed as contributors to depressive symptoms, although evidence in this group is scarce. Therefore, we aimed to evaluate the association between triglyceride and total cholesterol levels and depressive symptoms in medical students.<h4>Methods</h4>We conducted a cross-sectional study including 219 medical students from a public university in Mexico. Depressive symptoms were assessed using the CESD-7 scale, validated in the Mexican population. Fasting triglyceride and total cholesterol concentrations were measured with the Accutrend Plus a2025-01-01T00:00:00Z2025 Oct2026-05-14T03:17:25.258Z2026-05-14T03:12:03.804ZS-EPMC125626264114906010.3390/diseases13100326