<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Matsumoto R</submitter><funding>Yu Hikita</funding><funding>Tetsutaro Yamaguchi</funding><pagination>458</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC12562631</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>13(10)</volume><pubmed_abstract>&lt;b>Background/Objectives:&lt;/b> Multi-bracket appliances are essential in surgical orthodontic treatment, and perioperative oral management during orthognathic surgery is critical. Thorough plaque control, appropriate use of antibiotics, and shortening of operative time have been reported to be effective in preventing postoperative infections and ensuring surgical success. As highly invasive orthognathic surgery involving osteotomy may influence the postoperative oral microbiota, this study aimed to investigate the characteristics of and clarify the changes occurring in the salivary oral microbiota after orthognathic surgery. &lt;b>Methods:&lt;/b> The study included 14 patients (Group S; mean age 29.3 ± 9.8 years) who underwent surgical orthodontic treatment and 15 control patients (Group C; mean </pubmed_abstract><journal>Dentistry journal</journal><pubmed_title>Comparison of Long-Term Oral Bacterial Flora Before and After Orthognathic Surgery in Surgical Orthodontic Treatment.</pubmed_title><pmcid>PMC12562631</pmcid><funding_grant_id>24K20091</funding_grant_id><funding_grant_id>24K13185</funding_grant_id><pubmed_authors>Hosomichi K</pubmed_authors><pubmed_authors>Hikita Y</pubmed_authors><pubmed_authors>Matsumoto R</pubmed_authors><pubmed_authors>Yamaguchi T</pubmed_authors><pubmed_authors>Hatanaka R</pubmed_authors><pubmed_authors>Okuwaki S</pubmed_authors><pubmed_authors>Takahashi M</pubmed_authors><pubmed_authors>Koizumi S</pubmed_authors></additional><is_claimable>false</is_claimable><name>Comparison of Long-Term Oral Bacterial Flora Before and After Orthognathic Surgery in Surgical Orthodontic Treatment.</name><description>&lt;b>Background/Objectives:&lt;/b> Multi-bracket appliances are essential in surgical orthodontic treatment, and perioperative oral management during orthognathic surgery is critical. Thorough plaque control, appropriate use of antibiotics, and shortening of operative time have been reported to be effective in preventing postoperative infections and ensuring surgical success. As highly invasive orthognathic surgery involving osteotomy may influence the postoperative oral microbiota, this study aimed to investigate the characteristics of and clarify the changes occurring in the salivary oral microbiota after orthognathic surgery. &lt;b>Methods:&lt;/b> The study included 14 patients (Group S; mean age 29.3 ± 9.8 years) who underwent surgical orthodontic treatment and 15 control patients (Group C; mean </description><dates><release>2025-01-01T00:00:00Z</release><publication>2025 Oct</publication><modification>2026-05-14T03:20:22.779Z</modification><creation>2026-05-14T03:12:45.245Z</creation></dates><accession>S-EPMC12562631</accession><cross_references><pubmed>41149107</pubmed><doi>10.3390/dj13100458</doi></cross_references></HashMap>