{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Alves HCBR"],"funding":["Fundo de Amparo à Pesquisa"],"pagination":["1092"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12563574"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(10)"],"pubmed_abstract":["<h4>Background/objectives</h4>Single-phase CT angiography (sCTA) is widely used to assess collateral circulation in acute ischemic stroke, but its static nature can lead to an underestimation of collateral flow. Our study aimed to develop and validate a direct, qualitative dynamic CTA (dCTA) collateral score based on CTP source images, without the need for post-processing software, to provide a more accurate prognostic tool.<h4>Methods</h4>We retrospectively analyzed 112 patients with anterior circulation ischemic stroke from a prospective registry who underwent non-contrast CT, sCTA, and CTP within 8 h of onset. Collateral circulation was graded using a 4-point sCTA score and our novel 4-point dCTA score, which incorporates temporal filling patterns. We used linear regression to compare t"],"journal":["Brain sciences"],"pubmed_title":["Collateral Status Evaluation Using CT Angiography and Perfusion Source Images in Acute Stroke Patients."],"pmcid":["PMC12563574"],"funding_grant_id":["2016-2018"],"pubmed_authors":["Gagliardi RJ","Alves HCBR","Gagliardi V","da Rocha AJ","Dutra BG","Maia ACM","Pacheco FT"],"additional_accession":[]},"is_claimable":false,"name":"Collateral Status Evaluation Using CT Angiography and Perfusion Source Images in Acute Stroke Patients.","description":"<h4>Background/objectives</h4>Single-phase CT angiography (sCTA) is widely used to assess collateral circulation in acute ischemic stroke, but its static nature can lead to an underestimation of collateral flow. Our study aimed to develop and validate a direct, qualitative dynamic CTA (dCTA) collateral score based on CTP source images, without the need for post-processing software, to provide a more accurate prognostic tool.<h4>Methods</h4>We retrospectively analyzed 112 patients with anterior circulation ischemic stroke from a prospective registry who underwent non-contrast CT, sCTA, and CTP within 8 h of onset. Collateral circulation was graded using a 4-point sCTA score and our novel 4-point dCTA score, which incorporates temporal filling patterns. We used linear regression to compare t","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-05-14T03:17:59.218Z","creation":"2026-05-14T03:10:57.732Z"},"accession":"S-EPMC12563574","cross_references":{"pubmed":["41154187"],"doi":["10.3390/brainsci15101092"]}}