biostudies-literatureUnknown14(20)Hermann A<b>Background:</b> Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), serves as a major complication in critically ill patients receiving extracorporeal life support (ECLS). The primary aim of the study was to systematically determine the prevalence of cannula-associated DVT following ECLS in a mixed adult ICU population. <b>Methods:</b> In this prospective diagnostic study, performed at two ICUs at a tertiary university hospital, we included 101 patients undergoing ECLS between 2016 and 2021. DVT was assessed by vascular ultrasound within 72 h after decannulation or through post-mortem examination. PE was identified by computed tomography when clinically indicated or through post-mortem examination. Both univariate analysis and multivariableJournal of clinical medicine7241https://www.ebi.ac.uk/biostudies/studies/S-EPMC12565285biostudies-literatureCannula-Associated Deep Vein Thrombosis After Extracorporeal Life Support: A Prospective Diagnostic Study.PMC12565285Ristl RRobak OKlaeger JPBuchtele NKrais JSchoergenhofer CNagler BStommel AMStaudinger THermann ATremetsberger AMSchellongowski PfalseCannula-Associated Deep Vein Thrombosis After Extracorporeal Life Support: A Prospective Diagnostic Study.<b>Background:</b> Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), serves as a major complication in critically ill patients receiving extracorporeal life support (ECLS). The primary aim of the study was to systematically determine the prevalence of cannula-associated DVT following ECLS in a mixed adult ICU population. <b>Methods:</b> In this prospective diagnostic study, performed at two ICUs at a tertiary university hospital, we included 101 patients undergoing ECLS between 2016 and 2021. DVT was assessed by vascular ultrasound within 72 h after decannulation or through post-mortem examination. PE was identified by computed tomography when clinically indicated or through post-mortem examination. Both univariate analysis and multivariable2025-01-01T00:00:00Z2025 Oct2026-05-15T03:11:02.109Z2026-05-15T03:07:51.611ZS-EPMC125652854115611010.3390/jcm14207241