biostudies-literatureUnknown14(20)Piber N<b>Background/Objectives</b>: Obstruction of the Fontan pathway is a severe morbidity after total cavopulmonary connection (TCPC). This study aimed to evaluate the incidence and location of TCPC pathway obstruction and corresponding interventions. <b>Methods</b>: In all patients undergoing TCPC between 1994 and 2023, postoperative interventions for TCPC pathway obstruction were evaluated. Risk factors for TCPC pathway interventions were identified, and the impact of TCPC pathway interventions on late outcomes was analyzed. <b>Results</b>: Among 650 patients, 136 (21%) needed catheter/surgical interventions for TCPC pathway obstructions during the median duration of 0.2 (0.03-6.1) years postoperatively. Interventions comprised 128 catheters and 10 surgeries. Catheter intervention included 1Journal of clinical medicine7447https://www.ebi.ac.uk/biostudies/studies/S-EPMC12565572biostudies-literatureInterventions for Fontan Pathway Obstruction in Patients Following Total Cavopulmonary Connection.PMC12565572Schaeffer THeinisch PPHorer JGeorgiev SEwert PLemmen TRuda CPalm JOno MPiber NKrane MMatsubara MHager AfalseInterventions for Fontan Pathway Obstruction in Patients Following Total Cavopulmonary Connection.<b>Background/Objectives</b>: Obstruction of the Fontan pathway is a severe morbidity after total cavopulmonary connection (TCPC). This study aimed to evaluate the incidence and location of TCPC pathway obstruction and corresponding interventions. <b>Methods</b>: In all patients undergoing TCPC between 1994 and 2023, postoperative interventions for TCPC pathway obstruction were evaluated. Risk factors for TCPC pathway interventions were identified, and the impact of TCPC pathway interventions on late outcomes was analyzed. <b>Results</b>: Among 650 patients, 136 (21%) needed catheter/surgical interventions for TCPC pathway obstructions during the median duration of 0.2 (0.03-6.1) years postoperatively. Interventions comprised 128 catheters and 10 surgeries. Catheter intervention included 12025-01-01T00:00:00Z2025 Oct2026-05-14T03:11:25.599Z2026-05-14T03:08:45.236ZS-EPMC125655724115631510.3390/jcm14207447