{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Javanmardi J"],"funding":["Bundesministerium für Forschung, Technologie und Raumfahrt","Federal Ministry of Health"],"pagination":["2379"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12566045"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(10)"],"pubmed_abstract":["The COVID-19 pandemic has increased interest in wastewater-based epidemiology (WBE) as a reliable and cost-effective framework for monitoring the spread of microbes. However, WBE frameworks have rarely been applied to the study of fecal-oral transmissible diseases, except for poliomyelitis. Here, we investigated the presence of hepatitis A virus (HAV) and hepatitis E virus (HEV) in wastewater in Munich. We collected wastewater samples between July 2020 and November 2023. A total of 186 samples were processed using centrifugation and analyzed for HAV- and HEV-RNA using RT-qPCR. As a reference, we used notification data from clinically or laboratory-diagnosed hepatitis A and E cases. Lockdown stringency levels were derived from official documentation. Our results show that 87.6% of wastewate"],"journal":["Microorganisms"],"pubmed_title":["Continuous Circulation of Hepatitis E and A Viruses During COVID-19 Pandemic Lockdowns in Munich, Germany-Experience from Three Years of Wastewater Surveillance."],"pmcid":["PMC12566045"],"funding_grant_id":["031L0297E","1369-386"],"pubmed_authors":["Hasenauer J","Schemmerer M","Wallrafen-Sam K","Waldeck E","Hoelscher M","Schneider M","Wenzel JJ","Javanmardi J","Bohmer MM","Geldmacher C","Rubio-Acero R","Kletke T","Boehm B","Wieser A","Neusser J","Hoch M"],"additional_accession":[]},"is_claimable":false,"name":"Continuous Circulation of Hepatitis E and A Viruses During COVID-19 Pandemic Lockdowns in Munich, Germany-Experience from Three Years of Wastewater Surveillance.","description":"The COVID-19 pandemic has increased interest in wastewater-based epidemiology (WBE) as a reliable and cost-effective framework for monitoring the spread of microbes. However, WBE frameworks have rarely been applied to the study of fecal-oral transmissible diseases, except for poliomyelitis. Here, we investigated the presence of hepatitis A virus (HAV) and hepatitis E virus (HEV) in wastewater in Munich. We collected wastewater samples between July 2020 and November 2023. A total of 186 samples were processed using centrifugation and analyzed for HAV- and HEV-RNA using RT-qPCR. As a reference, we used notification data from clinically or laboratory-diagnosed hepatitis A and E cases. Lockdown stringency levels were derived from official documentation. Our results show that 87.6% of wastewate","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-05-15T03:17:35.621Z","creation":"2026-05-15T03:11:45.679Z"},"accession":"S-EPMC12566045","cross_references":{"pubmed":["41156838"],"doi":["10.3390/microorganisms13102379"]}}