{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["30(10)"],"submitter":["Fabi A"],"funding":["Dompé farmaceutici S.p.A., Milan, Italy"],"pubmed_abstract":["<h4>Background</h4>Cancer-related fatigue (CRF) is a common symptom in patients with locally advanced or metastatic breast cancer (LA/M BC) receiving taxane-based chemotherapy (CT). CRF is commonly assessed as a subjective experience by patient questionnaires, such as the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue. The aim of this study was to extend the validity of the FACIT-Fatigue and estimate clinically meaningful group-level differences in this patient population.<h4>Materials and methods</h4>This was a prospective, noninterventional, multinational study conducted in the United States and Italy from October 2021 to August 2023 in adult patients with LA/M BC eligible to receive cycle 1 of taxane-based CT. Patients completed a FACIT-Fatigue survey before starting C"],"journal":["The oncologist"],"pagination":["oyaf292"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12573256"],"repository":["biostudies-literature"],"pubmed_title":["Validation of the FACIT-Fatigue scale in patients with locally advanced or metastatic breast cancer."],"pmcid":["PMC12573256"],"pubmed_authors":["Minnella EM","Allegretti M","Gavioli EM","Fabi A","Lourdes L","Wakade R","Gandini C","Hager S"],"additional_accession":[]},"is_claimable":false,"name":"Validation of the FACIT-Fatigue scale in patients with locally advanced or metastatic breast cancer.","description":"<h4>Background</h4>Cancer-related fatigue (CRF) is a common symptom in patients with locally advanced or metastatic breast cancer (LA/M BC) receiving taxane-based chemotherapy (CT). CRF is commonly assessed as a subjective experience by patient questionnaires, such as the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue. The aim of this study was to extend the validity of the FACIT-Fatigue and estimate clinically meaningful group-level differences in this patient population.<h4>Materials and methods</h4>This was a prospective, noninterventional, multinational study conducted in the United States and Italy from October 2021 to August 2023 in adult patients with LA/M BC eligible to receive cycle 1 of taxane-based CT. Patients completed a FACIT-Fatigue survey before starting C","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T09:40:02.386Z","creation":"2026-05-15T03:11:59.923Z"},"accession":"S-EPMC12573256","cross_references":{"pubmed":["41006068"],"doi":["10.1093/oncolo/oyaf292"]}}