biostudies-literatureCazzaniga GMinistero della SaluteMinistero dell&apos;Università e della Ricerca798-804https://www.ebi.ac.uk/biostudies/studies/S-EPMC12573376biostudies-literatureUnknown78(11)<h4>Aim</h4>The digital transformation of the pathology laboratory is being continuously sustained by the introduction of innovative technologies promoting whole slide image (WSI)-based primary diagnosis. Here, we proposed a real-life benchmark of a pathology-dedicated medical monitor for the primary diagnosis of renal biopsies, evaluating the concordance between the 'traditional' microscope and commercial monitors using WSI from different scanners.<h4>Methods</h4>The College of American Pathologists WSI validation guidelines were used on 60 consecutive renal biopsies from three scanners (Aperio, 3DHISTECH and Hamamatsu) using pathology-dedicated medical grade (MG), professional grade (PG) and consumer-off-the-shelf (COTS) monitors, comparing results with the microscope diagnosis after a 2Journal of clinical pathologyBenchmarking digital displays (monitors) for histological diagnoses: the nephropathology use case.PMC12573376PNRR-MR1-2022-12375735Dipartimenti di Eccellenza 2023-2027 (l. 232/2016,GR-2021-12374235Pagni FMarletta SEccher ADei Tos APMascadri FCazzaniga GGambaro GCaputo AL'Imperio VGuidi GfalseBenchmarking digital displays (monitors) for histological diagnoses: the nephropathology use case.<h4>Aim</h4>The digital transformation of the pathology laboratory is being continuously sustained by the introduction of innovative technologies promoting whole slide image (WSI)-based primary diagnosis. Here, we proposed a real-life benchmark of a pathology-dedicated medical monitor for the primary diagnosis of renal biopsies, evaluating the concordance between the 'traditional' microscope and commercial monitors using WSI from different scanners.<h4>Methods</h4>The College of American Pathologists WSI validation guidelines were used on 60 consecutive renal biopsies from three scanners (Aperio, 3DHISTECH and Hamamatsu) using pathology-dedicated medical grade (MG), professional grade (PG) and consumer-off-the-shelf (COTS) monitors, comparing results with the microscope diagnosis after a 22025-01-01T00:00:00Z2025 Oct2026-06-05T10:53:24.088Z2026-06-05T03:06:46.59ZS-EPMC125733763853807610.1136/jcp-2024-209418