{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["24(1)"],"submitter":["Mohamed AO"],"pubmed_abstract":["<h4>Background</h4>Malaria diagnosis by Rapid Diagnostic Test (RDT) is challenged by the newly emerging histidine-rich protein 2 (HRP2) gene deletion in the Plasmodium falciparum species. The alternative lactate dehydrogenase (LDH)-dependent RDTs suffer from low sensitivity, and improvement in the sensitivity of LDH RDTs is the cornerstone for detecting the (HRP2) gene deletion species. This study aimed to evaluate a novel, improved Mologic Malaria Pf LDH-dependent RDT for the diagnosis of P. falciparum malaria in partnership with the Foundation for Innovative Diagnostics (FIND), Switzerland.<h4>Methods</h4>This is a descriptive cross-sectional study evaluating the clinical performance of the improved Mologic LDH- RDT in two rural sites in Khartoum state, Sudan. Five hundred patients prese"],"journal":["Malaria journal"],"pagination":["363"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12574065"],"repository":["biostudies-literature"],"pubmed_title":["Clinical evaluation of a novel Mologic malaria Plasmodium falciparum LDH-dependent lateral flow rapid diagnostic test diagnostic accuracy: a cross-sectional study, Sudan."],"pmcid":["PMC12574065"],"pubmed_authors":["Albsheer MM","Jebreel WMA","Hamid MMA","Elaagip A","Dittrich S","Mohamed AO","Mohammed FO","Ahmed SBA","Mustafa SA","Chamai M","Ahmed TME"],"additional_accession":[]},"is_claimable":false,"name":"Clinical evaluation of a novel Mologic malaria Plasmodium falciparum LDH-dependent lateral flow rapid diagnostic test diagnostic accuracy: a cross-sectional study, Sudan.","description":"<h4>Background</h4>Malaria diagnosis by Rapid Diagnostic Test (RDT) is challenged by the newly emerging histidine-rich protein 2 (HRP2) gene deletion in the Plasmodium falciparum species. The alternative lactate dehydrogenase (LDH)-dependent RDTs suffer from low sensitivity, and improvement in the sensitivity of LDH RDTs is the cornerstone for detecting the (HRP2) gene deletion species. This study aimed to evaluate a novel, improved Mologic Malaria Pf LDH-dependent RDT for the diagnosis of P. falciparum malaria in partnership with the Foundation for Innovative Diagnostics (FIND), Switzerland.<h4>Methods</h4>This is a descriptive cross-sectional study evaluating the clinical performance of the improved Mologic LDH- RDT in two rural sites in Khartoum state, Sudan. Five hundred patients prese","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T09:39:55.072Z","creation":"2026-05-15T03:11:57.466Z"},"accession":"S-EPMC12574065","cross_references":{"pubmed":["41163208"],"doi":["10.1186/s12936-025-05609-x"]}}