{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(10)"],"submitter":["Arabi YM"],"pubmed_abstract":["<h4>Introduction</h4>Deep vein thrombosis (DVT) in critically ill patients is often undetected. However, it is unclear whether ultrasound surveillance for early detection of DVT in high-risk medical-surgical intensive care unit (ICU) patients improves patients' outcomes. The DETECT trial (Diagnosing deep-vein thrombosis early in critically ill patients) evaluates the effect of twice-weekly bilateral lower limb ultrasound compared to usual care on 90-day mortality of critically ill adult patients admitted to medical, surgical and trauma ICUs.<h4>Methods and analysis</h4>The DETECT trial is an international, parallel-group, open-label, randomised trial, which will recruit 1800 critically ill adults from over 14 hospitals in Saudi Arabia and Kuwait. Eligible patients will be allocated to twic"],"journal":["BMJ open"],"pagination":["e104468"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12574397"],"repository":["biostudies-literature"],"pubmed_title":["Diagnosing deep vein thrombosis early in critically ill patients (DETECT) trial: a protocol for a randomised controlled trial."],"pmcid":["PMC12574397"],"pubmed_authors":["Wael M","Kharaba A","Alnasrallah S","Ahmed MG","Alhemiani S","Maghrabi K","Amin SN","AliAlqahtani MS","Alshahrani MS","Alqahtani S","Mallisho A","Matrouk AA","Ibrahim FM","Alqahtani M","Al-Anazi H","Aldouhan J","Ahmed MA","Alfaghm S","Alfilfil W","Al-Dawood A","Alkhaldi F","Al-Rasheadi MS","Almousa AM","Badawy EI","Almuteb J","Alenzi M","Bouderar I","Abanumay F","Bubbas S","Alhazzani W","Abuhaimed JM","Chalabi J","Al-Fares AA","Elhady M","Orabi OA","Saudi Critical Care Trials Group","Bokhari MF","Bin Humaid F","Mutari AA","Abdulgader RA","Al-Hameed F","Aldabas M","Mapusao C","Ayon S","Abuillah W","Jasem BA","Al-Aqeeli A","AlHumedi H","Beji OH","Ababtain AA","Hassanin IM","Piero M","Alenezi F","Nawaf S","Brembali MJ","Al Humedi HI","Eldin DS","Alshahrani MSS","AlHumaidan A","Alnefaie B","Albinali M","Sadat M","Almazyad G","Arabi YM","AlQahtani RM","Alahmary F","Ardah HI","Al-Filfil WAM","Asonto LP","AlHamzah M","AlQahtani SY","Alsakan A","Elfaki O","Alsomali H","Barnawi R","Abduljabbar AH","Humaid FB","Alsomali M","Khyyat M","Nasef A","Blazquez CH","Al-Obaidly F","Altuwayjiri K","Alattas AA","Al-Enazi NS","Buabbas SF","Rasool G","Hazem W","Baisas M","Algathmy H","Alahmari AM","Neimatalla M","Noor M","Alolit S","Chamaa MA","Almehmadi SF","SaeedAbo-Zaid MF","Alageel NA","Almarshadi S","Al Tamimi A","Aldohan MM","Johani AA","Tamimi AA","Ahmed EM","Algethamy H","Almuthaybiri FF","Almutairi BS","Amer M","Almoghamsy Y"],"additional_accession":[]},"is_claimable":false,"name":"Diagnosing deep vein thrombosis early in critically ill patients (DETECT) trial: a protocol for a randomised controlled trial.","description":"<h4>Introduction</h4>Deep vein thrombosis (DVT) in critically ill patients is often undetected. However, it is unclear whether ultrasound surveillance for early detection of DVT in high-risk medical-surgical intensive care unit (ICU) patients improves patients' outcomes. The DETECT trial (Diagnosing deep-vein thrombosis early in critically ill patients) evaluates the effect of twice-weekly bilateral lower limb ultrasound compared to usual care on 90-day mortality of critically ill adult patients admitted to medical, surgical and trauma ICUs.<h4>Methods and analysis</h4>The DETECT trial is an international, parallel-group, open-label, randomised trial, which will recruit 1800 critically ill adults from over 14 hospitals in Saudi Arabia and Kuwait. Eligible patients will be allocated to twic","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T09:31:32.019Z","creation":"2026-05-15T03:12:51.879Z"},"accession":"S-EPMC12574397","cross_references":{"pubmed":["41161824"],"doi":["10.1136/bmjopen-2025-104468"]}}