biostudies-literatureUnknown7Felicianna<h4>Introduction</h4>Plant cell culture (PCC) technology is currently being developed to produce plant foods partially decoupled from traditional agriculture practices. By now, the safety of the ingredients produced by PCC technology for food or nutritional purposes has to be tested.<h4>Materials and methods</h4>In this study, the oral safety and toxicity of two novel PCCs, scurvy grass (SG) (Cochlearia danica) and rowan (RW) (Sorbus aucuparia), and to characterize the macro- and micronutrient quality, including proteomic profiles, to identify potential allergens.<h4>Results</h4>Nutritional composition analysis showed that both SG and RW PCCs profiles are comparable to other berry cell lines with a good amount of protein, dietary fibre and vitamins. Potential allergens were identified via Frontiers in toxicology1655489https://www.ebi.ac.uk/biostudies/studies/S-EPMC12580138biostudies-literatureToxicological and nutritional evaluation of plant cell cultures from scurvy grass (<i>Cochlearia danica</i>) and rowan (<i>Sorbus aucuparia</i>).PMC12580138Gomez-Gallego CZhang FIannone VFeliciannaNordlund EKolehmainen MCheung HLRosa-Sibakov NLeung HKMLo EKKIsmaiah MJEl-Nezami HRischer HfalseToxicological and nutritional evaluation of plant cell cultures from scurvy grass (<i>Cochlearia danica</i>) and rowan (<i>Sorbus aucuparia</i>).<h4>Introduction</h4>Plant cell culture (PCC) technology is currently being developed to produce plant foods partially decoupled from traditional agriculture practices. By now, the safety of the ingredients produced by PCC technology for food or nutritional purposes has to be tested.<h4>Materials and methods</h4>In this study, the oral safety and toxicity of two novel PCCs, scurvy grass (SG) (Cochlearia danica) and rowan (RW) (Sorbus aucuparia), and to characterize the macro- and micronutrient quality, including proteomic profiles, to identify potential allergens.<h4>Results</h4>Nutritional composition analysis showed that both SG and RW PCCs profiles are comparable to other berry cell lines with a good amount of protein, dietary fibre and vitamins. Potential allergens were identified via 2025-01-01T00:00:00Z20252026-06-05T11:54:50.182Z2026-05-16T03:12:50.601ZS-EPMC125801384118987610.3389/ftox.2025.1655489