{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Wang T"],"pubmed_abstract":["<h4>Objective</h4>This study aimed to systematically analyze the morbidity and mortality of infectious diarrhea in children under 14 years old caused by pathogenic microorganisms globally and their temporal trends.<h4>Methods</h4>This study was a retrospective cross-sectional analysis using the database provided by the Global Burden of Disease 2021 (GBD 2021). The mortality, morbidity, and disability-adjusted life years (DALYs) of childhood diarrhea from 1990 to 2021 were stratified and analyzed using multivariate regression models and the calculation of estimated annual percentage change (EAPC).<h4>Results</h4>In 2021, the total number of cases of diarrhea in children aged 0-14 years worldwide was 168.73 million. The number of cases was highest in low- and medium-SDI regions, and the inci"],"journal":["Frontiers in medicine"],"pagination":["1676249"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12580197"],"repository":["biostudies-literature"],"pubmed_title":["Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021."],"pmcid":["PMC12580197"],"pubmed_authors":["Li H","Sang X","Lu W","Li S","Wang T","Ren Y","Xu T","Huang Q","Wang L","Xiao A","Wu X"],"additional_accession":[]},"is_claimable":false,"name":"Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.","description":"<h4>Objective</h4>This study aimed to systematically analyze the morbidity and mortality of infectious diarrhea in children under 14 years old caused by pathogenic microorganisms globally and their temporal trends.<h4>Methods</h4>This study was a retrospective cross-sectional analysis using the database provided by the Global Burden of Disease 2021 (GBD 2021). The mortality, morbidity, and disability-adjusted life years (DALYs) of childhood diarrhea from 1990 to 2021 were stratified and analyzed using multivariate regression models and the calculation of estimated annual percentage change (EAPC).<h4>Results</h4>In 2021, the total number of cases of diarrhea in children aged 0-14 years worldwide was 168.73 million. The number of cases was highest in low- and medium-SDI regions, and the inci","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-05T11:55:01.488Z","creation":"2026-05-16T03:12:57.482Z"},"accession":"S-EPMC12580197","cross_references":{"pubmed":["41189886"],"doi":["10.3389/fmed.2025.1676249"]}}