biostudies-literatureUnknown35(6)Stratmann M<h4>Background</h4>Endocrine disrupting chemicals (EDCs) can cross the placenta and thereby expose the fetus, which may lead to developmental consequences. It is still unclear which chemicals are of concern regarding neurodevelopment and specifically behaviour, when being exposed to a mixture.<h4>Objective</h4>The objective is to determine associations between prenatal exposure to EDCs and behavioural difficulties. Furthermore, we investigated sex-specific associations and determined chemicals of concern in significant regressions.<h4>Methods</h4>Associations between prenatal exposure to EDCs (both as single compounds and their mixtures) and behavioural outcomes using the Strengths and Difficulties Questionnaire (SDQ) were estimated in 607 mother-child pairs in the Swedish Environmental LoJournal of exposure science & environmental epidemiology981-991https://www.ebi.ac.uk/biostudies/studies/S-EPMC12583134biostudies-literaturePrenatal exposure to endocrine disrupting chemicals and the association with behavioural difficulties in 7-year-old children in the SELMA study.PMC12583134Stratmann MKiviranta HMarinopoulou MGennings CLindh COzel FBornehag CGfalsePrenatal exposure to endocrine disrupting chemicals and the association with behavioural difficulties in 7-year-old children in the SELMA study.<h4>Background</h4>Endocrine disrupting chemicals (EDCs) can cross the placenta and thereby expose the fetus, which may lead to developmental consequences. It is still unclear which chemicals are of concern regarding neurodevelopment and specifically behaviour, when being exposed to a mixture.<h4>Objective</h4>The objective is to determine associations between prenatal exposure to EDCs and behavioural difficulties. Furthermore, we investigated sex-specific associations and determined chemicals of concern in significant regressions.<h4>Methods</h4>Associations between prenatal exposure to EDCs (both as single compounds and their mixtures) and behavioural outcomes using the Strengths and Difficulties Questionnaire (SDQ) were estimated in 607 mother-child pairs in the Swedish Environmental Lo2025-01-01T00:00:00Z2025 Nov2026-06-05T10:44:20.188Z2026-05-16T03:08:13.752ZS-EPMC125831343970246510.1038/s41370-024-00739-x