{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Chen H"],"pubmed_abstract":["<h4>Background</h4>Identifying the cause of extreme thrombocytosis is important, but few data exist. This study aimed to analyze the etiology of extreme thrombocytosis and its influence on coagulation function.<h4>Methods</h4>We performed a ten-year retrospective study that included patients with platelet counts >1,000 × 10<sup>9</sup>/L. The etiology of extreme thrombocytosis was analyzed by physicians and compared between subgroups, which were stratified by department, age and sex. We also collected the coagulation function of inpatients, including the prothrombin time (PT), international normalized ratio, partial thromboplastin time ratio, prothrombin activity, activated partial thromboplastin time (APTT), fibrinogen, thrombin time and D-dimer, when patients were under extreme thrombocy"],"journal":["Frontiers in medicine"],"pagination":["1650704"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12588944"],"repository":["biostudies-literature"],"pubmed_title":["Etiology of patients with extreme thrombocytosis and its association with coagulation function: 10-year experience in a tertiary hospital."],"pmcid":["PMC12588944"],"pubmed_authors":["Huang S","Chen Q","Zhang Z","Chen H","Wu G","Yu Z","Ying M"],"additional_accession":[]},"is_claimable":false,"name":"Etiology of patients with extreme thrombocytosis and its association with coagulation function: 10-year experience in a tertiary hospital.","description":"<h4>Background</h4>Identifying the cause of extreme thrombocytosis is important, but few data exist. This study aimed to analyze the etiology of extreme thrombocytosis and its influence on coagulation function.<h4>Methods</h4>We performed a ten-year retrospective study that included patients with platelet counts >1,000 × 10<sup>9</sup>/L. The etiology of extreme thrombocytosis was analyzed by physicians and compared between subgroups, which were stratified by department, age and sex. We also collected the coagulation function of inpatients, including the prothrombin time (PT), international normalized ratio, partial thromboplastin time ratio, prothrombin activity, activated partial thromboplastin time (APTT), fibrinogen, thrombin time and D-dimer, when patients were under extreme thrombocy","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-18T03:15:15.905Z","creation":"2026-05-18T03:08:31.111Z"},"accession":"S-EPMC12588944","cross_references":{"pubmed":["41210867"],"doi":["10.3389/fmed.2025.1650704"]}}