{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(11 Pt 1)"],"submitter":["Ozaki S"],"pubmed_abstract":["<h4>Background</h4>Introduced in 2007, the Ozaki procedure-templated cusp replacement with autologous pericardium-is a new option for treating aortic valve disease. Mid-term outcomes and valve performance have not yet been reported.<h4>Objectives</h4>This study assesses longitudinal hemodynamics, left ventricular reverse remodeling, reoperation, and survival in the original Ozaki cohort.<h4>Methods</h4>1,196 patients underwent Ozaki procedures (60% male, age 11-90 years) at Toho University Ohashi Medical Center from April 2007 to May 2021: 2.4% had infective endocarditis, 27% had bicuspid valves, 54% had aortic stenosis, 24% had aortic regurgitation, 7.3% had mixed lesions, and 46% underwent concomitant procedures. Clinical outcomes, echocardiograms, and follow-up data (50% followed >3.2 y"],"journal":["JACC. Advances"],"pagination":["102156"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12589979"],"repository":["biostudies-literature"],"pubmed_title":["Mid-Term Experience With 1,196 Ozaki Procedures."],"pmcid":["PMC12589979"],"pubmed_authors":["Takatoo M","Shimura S","Goda M","Ozaki S","Hoshino Y","Hayama H","Rajeswaran J","Svensson LG","Kiyohara N","Unai S","Pettersson GB","Frankel WC","Harb SC","Blackstone EH"],"additional_accession":[]},"is_claimable":false,"name":"Mid-Term Experience With 1,196 Ozaki Procedures.","description":"<h4>Background</h4>Introduced in 2007, the Ozaki procedure-templated cusp replacement with autologous pericardium-is a new option for treating aortic valve disease. Mid-term outcomes and valve performance have not yet been reported.<h4>Objectives</h4>This study assesses longitudinal hemodynamics, left ventricular reverse remodeling, reoperation, and survival in the original Ozaki cohort.<h4>Methods</h4>1,196 patients underwent Ozaki procedures (60% male, age 11-90 years) at Toho University Ohashi Medical Center from April 2007 to May 2021: 2.4% had infective endocarditis, 27% had bicuspid valves, 54% had aortic stenosis, 24% had aortic regurgitation, 7.3% had mixed lesions, and 46% underwent concomitant procedures. Clinical outcomes, echocardiograms, and follow-up data (50% followed >3.2 y","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-07-15T11:16:14.913Z","creation":"2026-07-04T03:11:48.365Z"},"accession":"S-EPMC12589979","cross_references":{"pubmed":["41124984"],"doi":["10.1016/j.jacadv.2025.102156"]}}