biostudies-literatureUnknown64(11)Lee JEFonds de Recherche Santé QuébecCanadian Initiative for Outcomes in Rheumatology Care<h4>Objective</h4>To evaluate the effect of an educational tool on preeclampsia knowledge, as well as aspirin (ASA) use and adherence in pregnant SLE women.<h4>Methods</h4>A two-arm parallel randomized controlled trial was conducted recruiting pregnant SLE women up to 17 weeks' gestation. Participants were randomly assigned to receive either usual-care alone or usual-care plus the tool (laminated card incorporating infographics on preeclampsia in SLE and ASA for prevention). The primary outcome was difference in preeclampsia knowledge scores at the second-trimester visit.<h4>Results</h4>Of 73 women included, 38 were randomized to the intervention. In the primary analysis of ongoing pregnancies, increase in the mean preeclampsia knowledge scores was 4.0 points (95% CI: 2.4, 5.6) in the inteRheumatology (Oxford, England)5707-5715https://www.ebi.ac.uk/biostudies/studies/S-EPMC12596062biostudies-literatureAn educational tool to improve PREeclamPsia knowledge and Aspirin adheRence in lupus prEgnancies: the PREPARE trial.PMC12596062Urowitz MBLee JEBernatsky SMendel ALegge ALaskin CAVinet EClarke AETouma ZHanly JGMalhame IFortin PRPeschken CBarber MRWfalseAn educational tool to improve PREeclamPsia knowledge and Aspirin adheRence in lupus prEgnancies: the PREPARE trial.<h4>Objective</h4>To evaluate the effect of an educational tool on preeclampsia knowledge, as well as aspirin (ASA) use and adherence in pregnant SLE women.<h4>Methods</h4>A two-arm parallel randomized controlled trial was conducted recruiting pregnant SLE women up to 17 weeks' gestation. Participants were randomly assigned to receive either usual-care alone or usual-care plus the tool (laminated card incorporating infographics on preeclampsia in SLE and ASA for prevention). The primary outcome was difference in preeclampsia knowledge scores at the second-trimester visit.<h4>Results</h4>Of 73 women included, 38 were randomized to the intervention. In the primary analysis of ongoing pregnancies, increase in the mean preeclampsia knowledge scores was 4.0 points (95% CI: 2.4, 5.6) in the inte2025-01-01T00:00:00Z2025 Nov2026-07-15T11:20:54.441Z2026-07-04T03:11:30.479ZS-EPMC125960624057832310.1093/rheumatology/keaf334