{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["47(1)"],"submitter":["Fan C"],"pubmed_abstract":["Our study aimed at assessing the impact of β-blocker treatment on the mortality of patients with sepsis-associated acute kidney injury (SA-AKI). Clinical data for patients with SA-AKI were collected from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Baseline characteristics between β-blocker users and non-users were adjusted through propensity score matching (PSM). Kaplan-Meier curves and the Cox proportional hazards model were employed to analyze the relationship between β-blocker use and mortality, with the primary outcome being 30-day mortality. This study included data from 8,620 patients, with 3,159 receiving treatment and 5,461 not. After PSM, 2,896 matched pairs were created. The analysis revealed that 30-day (hazard ratio [HR]: 0.58, 95% CI: 0.52-0.65; <i>p</"],"journal":["Renal failure"],"pagination":["2562447"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12599005"],"repository":["biostudies-literature"],"pubmed_title":["Impact of β-blockers on mortality in sepsis-associated acute kidney injury: a retrospective propensity score-matched analysis."],"pmcid":["PMC12599005"],"pubmed_authors":["Duan J","Guo W","Wang H","Yan Y","Zheng G","Fan C","Yang F","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Impact of β-blockers on mortality in sepsis-associated acute kidney injury: a retrospective propensity score-matched analysis.","description":"Our study aimed at assessing the impact of β-blocker treatment on the mortality of patients with sepsis-associated acute kidney injury (SA-AKI). Clinical data for patients with SA-AKI were collected from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Baseline characteristics between β-blocker users and non-users were adjusted through propensity score matching (PSM). Kaplan-Meier curves and the Cox proportional hazards model were employed to analyze the relationship between β-blocker use and mortality, with the primary outcome being 30-day mortality. This study included data from 8,620 patients, with 3,159 receiving treatment and 5,461 not. After PSM, 2,896 matched pairs were created. The analysis revealed that 30-day (hazard ratio [HR]: 0.58, 95% CI: 0.52-0.65; <i>p</","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-05T12:25:59.393Z","creation":"2026-05-16T03:11:53.512Z"},"accession":"S-EPMC12599005","cross_references":{"pubmed":["41022073"],"doi":["10.1080/0886022X.2025.2562447"]}}