{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Zerna C"],"pubmed_abstract":["BackgroundTo compare the benefit of endovascular treatment(EVT) in acute ischemic stroke(AIS) patients with large vessel occlusion(LVO) presenting > 6 h from last known well outside a clinical trial setting to best medical management and to EVT in a randomized trial setting.MethodsData from a retrospective multicenter cohort study (ESCAPE-LATE) of AIS-LVO patients treated with EVT beyond 6 hours from last known well at former ESCAPE trial sites were pooled with historical data from ESCAPE trial late time window patients. Unadjusted and adjusted 90-day modified Rankin Scale (mRS) score was compared between ESCAPE-LATE patients, ESCAPE late time window EVT arm and control arm patients.ResultsA total of 249 patients were included in the analysis: 200 ESCAPE-LATE patients (for 141 of whom 90-d"],"journal":["Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences"],"pagination":["15910199251347782"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12602283"],"repository":["biostudies-literature"],"pubmed_title":["Endovascular treatment vs. best medical management for late window ischemic stroke patients with large vessel occlusion."],"pmcid":["PMC12602283"],"pubmed_authors":["Puetz V","van Adel B","Graham B","Yu AY","Hill MD","McTaggart RA","Frei DF","Harrison E","Pereira V","Kaiser DP","Goyal M","Shankar JJ","Zerna C","Kleinig TJ","Ospel J"],"additional_accession":[]},"is_claimable":false,"name":"Endovascular treatment vs. best medical management for late window ischemic stroke patients with large vessel occlusion.","description":"BackgroundTo compare the benefit of endovascular treatment(EVT) in acute ischemic stroke(AIS) patients with large vessel occlusion(LVO) presenting > 6 h from last known well outside a clinical trial setting to best medical management and to EVT in a randomized trial setting.MethodsData from a retrospective multicenter cohort study (ESCAPE-LATE) of AIS-LVO patients treated with EVT beyond 6 hours from last known well at former ESCAPE trial sites were pooled with historical data from ESCAPE trial late time window patients. Unadjusted and adjusted 90-day modified Rankin Scale (mRS) score was compared between ESCAPE-LATE patients, ESCAPE late time window EVT arm and control arm patients.ResultsA total of 249 patients were included in the analysis: 200 ESCAPE-LATE patients (for 141 of whom 90-d","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T15:13:39.192Z","creation":"2026-05-18T03:12:29.24Z"},"accession":"S-EPMC12602283","cross_references":{"pubmed":["41212518"],"doi":["10.1177/15910199251347782"]}}