{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen X"],"funding":["Carl Zeiss Vision","Tianjin Key Medical Discipline (Specialty) Construction Project"],"pagination":["929-938"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12604440"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["103(8)"],"pubmed_abstract":["Purpose
To evaluate the effectiveness of 12 months of spectacle lens wear incorporating cylindrical annular refractive elements (CARE) in slowing myopia progression compared to single vision (SV) spectacle wear.Methods
In an ongoing 2-year prospective, double-masked, multi-centre clinical trial, 240 Chinese children aged 6-13 years, spherical equivalent refractive error (SE) -0.75 D to -5.00 D were randomised to one of three groups of 80 participants each to wear: SV spectacle lens (N = 80), CARE spectacles (7 mm central clear zone surrounded by treatment zone incorporating CARE with mean surface power of +4.6 D) and CARE S (9 mm central clear zone surrounded by treatment zone comprising CARE with mean surface power of +3.8 D). Cycloplegic SE and axial length (AL) were meas"],"journal":["Acta ophthalmologica"],"pubmed_title":["Slowing myopia progression with cylindrical annular refractive elements (CARE) spectacle lenses-Year 1 results from a 2-year prospective, multi-centre trial."],"pmcid":["PMC12604440"],"funding_grant_id":["TJYXZDXK-016A"],"pubmed_authors":["Wu M","Yang Y","Rifai K","Boeck-Maier C","Yu C","Zhu Y","Chen X","Wahl S","Li L","Sankaridurg P","Ohlendorf A"],"additional_accession":[]},"is_claimable":false,"name":"Slowing myopia progression with cylindrical annular refractive elements (CARE) spectacle lenses-Year 1 results from a 2-year prospective, multi-centre trial.","description":"Purpose
To evaluate the effectiveness of 12 months of spectacle lens wear incorporating cylindrical annular refractive elements (CARE) in slowing myopia progression compared to single vision (SV) spectacle wear.Methods
In an ongoing 2-year prospective, double-masked, multi-centre clinical trial, 240 Chinese children aged 6-13 years, spherical equivalent refractive error (SE) -0.75 D to -5.00 D were randomised to one of three groups of 80 participants each to wear: SV spectacle lens (N = 80), CARE spectacles (7 mm central clear zone surrounded by treatment zone incorporating CARE with mean surface power of +4.6 D) and CARE S (9 mm central clear zone surrounded by treatment zone comprising CARE with mean surface power of +3.8 D). Cycloplegic SE and axial length (AL) were meas","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-07-15T12:18:05.578Z","creation":"2026-07-04T03:13:04.315Z"},"accession":"S-EPMC12604440","cross_references":{"pubmed":["39548605"],"doi":["10.1111/aos.16795"]}}