{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cardona L"],"funding":["Swiss National Science Foundation"],"pagination":["1650167"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12604563"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16"],"pubmed_abstract":["Polyphosphate-accumulating organisms (PAOs) play a crucial role in enhanced biological phosphorus removal (EBPR) processes. In addition to biosynthesis, they rely on phosphate for energy generation. However, <i>Candidatus</i> Accumulibacter, a model PAO, has been shown to adapt to low phosphate conditions by switching to a glycogen-accumulating metabolism (GAM), with variable success across genus members and experiments. This study aimed to explore the metabolic shift of several <i>Accumulibacter</i> species subjected to low-phosphate concentration in different operating conditions using metatranscriptomics analysis. Furthermore, the study enabled a comparison of the transcriptomic profiles of <i>Accumulibacter</i> with those of <i>Propionivibrio</i>, a glycogen-accumulating organism typic"],"journal":["Frontiers in microbiology"],"pubmed_title":["Comparative transcription profiles of &lt;i&gt;Candidatus&lt;/i&gt; Accumulibacter and &lt;i&gt;Propionivibrio&lt;/i&gt; under phosphate limitation in sequencing batch reactors."],"pmcid":["PMC12604563"],"funding_grant_id":["180575"],"pubmed_authors":["Ramirez PNR","Cardona L","Adler A","Holliger C"],"additional_accession":[]},"is_claimable":false,"name":"Comparative transcription profiles of &lt;i&gt;Candidatus&lt;/i&gt; Accumulibacter and &lt;i&gt;Propionivibrio&lt;/i&gt; under phosphate limitation in sequencing batch reactors.","description":"Polyphosphate-accumulating organisms (PAOs) play a crucial role in enhanced biological phosphorus removal (EBPR) processes. In addition to biosynthesis, they rely on phosphate for energy generation. However, <i>Candidatus</i> Accumulibacter, a model PAO, has been shown to adapt to low phosphate conditions by switching to a glycogen-accumulating metabolism (GAM), with variable success across genus members and experiments. This study aimed to explore the metabolic shift of several <i>Accumulibacter</i> species subjected to low-phosphate concentration in different operating conditions using metatranscriptomics analysis. Furthermore, the study enabled a comparison of the transcriptomic profiles of <i>Accumulibacter</i> with those of <i>Propionivibrio</i>, a glycogen-accumulating organism typic","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-05T12:56:01.091Z","creation":"2026-05-17T03:08:03.482Z"},"accession":"S-EPMC12604563","cross_references":{"pubmed":["41229682"],"doi":["10.3389/fmicb.2025.1650167"]}}