biostudies-literatureUnknown29(1)Blanchard F<h4>Background</h4>The administration of sedatives and analgesics in intensive care units (ICUs) has evolved significantly over the past 20 years, shifting from deep to light sedation strategies to minimize adverse effects. Despite this shift, substantial variability persists in sedation-analgesia practices. This study aimed to provide an updated national overview of sedation-analgesia management with a focus on discomfort assessment practices, including pain, delirium, anxiety, thirst, mood, and sleep disorders.<h4>Methods</h4>This was a one-day, multicenter, cross-sectional study conducted in French ICUs. Data were collected from all adult patients hospitalized in the ICU on the study day. A Unit-level survey documented ICU characteristics and sedation-analgesia protocols. Patient-level Critical care (London, England)483https://www.ebi.ac.uk/biostudies/studies/S-EPMC12606798biostudies-literatureEpidemiology of pain, delirium, psychiatric disorders, discomfort and sedation-analgesia management in the intensive care unit: a one-day nationwide study.PMC12606798Mervant MFrasca DJames AHirwe AGouzien LBehouche ABadet MBarage ALeone MGarel PBerger AAtchade EPichon NMartinet CWicky PHThille AHerzog NRodrigues AAllaouchiche BSouletie LDelbove AMathieu DVivier EKowalski BChevrel GMira JPHenry CLevrat QDesmeulles IRambaud TThierry SBavozet FGourier SSouwein BGette SLevrat AGillart TCouadau EAntoine MGannac AMertes PMKada KSitbon ABeuret PBrottier MRamin RAsehnoune KVerdin MVincent MCohen YRozec BFedun YGrouille JGeorges HAuvet ADessertaine GLautrette AAmathieu RVatignez TMiard CAnnane DGrigoresco BHeming NMuccio SCadoz CMarquer BGerald CFagot-Gandet FMonnin MAudibert JJaquet PVelly LBiais MGaubert ARineau ECombes AVivet BESPRIT Study groupPili-Floury SBesnier EValette MLegros VBaldesi OSerge CBrassard BLaurent FDuvivier JClavier TVerdonk FLescroart MGrillet GCompere VLukaszewicz ACSaint-Genis QPiquet EGenty TChanques GHanouz JLDa Silva DBlanchard FRghioui KFrancis RMongardon NDupre CLakhal KBrunin YTounsi RPerez PBenoit VCamozzi TKrid OBianchi ADecavele MBlum LDesnos CBeilvert MBrunin GHuot BLeray JChaoui KBougle AMartino FBourion AABouju PFoucault CMarchalot AHoffmann CRichard JCRiu BLaffon MRadjou AConstantin JMOchin EDuranteau OVardon FBruneel FMorel JUrli MEscudier EDuranteau JGuichon CTavernier BDemoule AVarillon CJacquens ARayar JFrachea ALMedjani MKempf JBouras MBoutonnet MDegos VAries PGakuba CCharre SBaudouin LFartoukh MGarin ADopeux LSophie DMezidi MJung BSauvajon DTrouiller PGaubert-Duclos JBlazejewski CClerc SRuiz JSimeone PBressan AGSusset VSimon GBouhemad BFutier EMonchi MDucros LLe Meur AHoppe MACollange OKapandji NSavalle MChelly JJurado ATamlihat YAEljezi VMontravers PLuyt CECrotet MChousterman BTurbil EVan Der Meersch GTrebbia GDucos GFrancois SRigaud JPJaber SDevautour CTamion FCayot SGergaud SHoff JBruno LDewitte ASoufane MDesbordes JDas VHausermann MHPlattier RCholley BHilaire FDesvergez ANicolas DLorber JSavary BGouin PMoussa MDVerbrackel VBreteau INguyen MDureau AFSchoeffler MPiton GOuchenir AFonseque ELangeron OHuz CLasocki SVieille TPlaud BChabanne RfalseEpidemiology of pain, delirium, psychiatric disorders, discomfort and sedation-analgesia management in the intensive care unit: a one-day nationwide study.<h4>Background</h4>The administration of sedatives and analgesics in intensive care units (ICUs) has evolved significantly over the past 20 years, shifting from deep to light sedation strategies to minimize adverse effects. Despite this shift, substantial variability persists in sedation-analgesia practices. This study aimed to provide an updated national overview of sedation-analgesia management with a focus on discomfort assessment practices, including pain, delirium, anxiety, thirst, mood, and sleep disorders.<h4>Methods</h4>This was a one-day, multicenter, cross-sectional study conducted in French ICUs. Data were collected from all adult patients hospitalized in the ICU on the study day. A Unit-level survey documented ICU characteristics and sedation-analgesia protocols. Patient-level 2025-01-01T00:00:00Z2025 Nov2026-06-05T14:58:38.562Z2026-05-18T03:12:57.118ZS-EPMC126067984121989210.1186/s13054-025-05654-7