biostudies-literatureAnyigba CAWorld Bank African Centres of Excellence and a DELTAS African Initiative3468https://www.ebi.ac.uk/biostudies/studies/S-EPMC12608925biostudies-literatureUnknown17(21)<h4>Background/objectives</h4>Breast cancer incidence is increasing in younger Ghanaian women. However, few epidemiological studies have evaluated the modifiable risk factors in this population. Additionally, these studies have classified breast cancer in Ghanaian women based on the global menopausal case classification. This study reclassified premenopausal and postmenopausal breast cancer in a Ghanaian cohort, assessing the risk factors using the observed menopausal age in Ghanaian women of 48 years, rather than the global standard of 50 years.<h4>Methods</h4>Women diagnosed with breast cancer and scheduled for surgery from December 2018 to March 2023 were recruited across four hospitals in Ghana for the Ghana Breast Cancer Omics Project (BCOPGh), and data were collected using a questionCancersReclassifying Menopausal Breast Cancer and Assessing Non-Genetic Risk Factors in Ghanaian Women: Insights from a Cohort Study.PMC12608925DEL-22-014: AwandareUdoakang AJAsamoah CDEdusei LAwandare GANsaful JAnyigba CAFrempong HAzusiyine VADedey FWeigel RJClegg-Lamptey JNLamptey ELSiame CTwumasi APaemka LArmah RfalseReclassifying Menopausal Breast Cancer and Assessing Non-Genetic Risk Factors in Ghanaian Women: Insights from a Cohort Study.<h4>Background/objectives</h4>Breast cancer incidence is increasing in younger Ghanaian women. However, few epidemiological studies have evaluated the modifiable risk factors in this population. Additionally, these studies have classified breast cancer in Ghanaian women based on the global menopausal case classification. This study reclassified premenopausal and postmenopausal breast cancer in a Ghanaian cohort, assessing the risk factors using the observed menopausal age in Ghanaian women of 48 years, rather than the global standard of 50 years.<h4>Methods</h4>Women diagnosed with breast cancer and scheduled for surgery from December 2018 to March 2023 were recruited across four hospitals in Ghana for the Ghana Breast Cancer Omics Project (BCOPGh), and data were collected using a question2025-01-01T00:00:00Z2025 Oct2026-05-18T03:14:14.568Z2026-05-18T03:12:07.003ZS-EPMC126089254122826110.3390/cancers17213468