biostudies-literatureUnknown15(52)Huang CYThree new scalarane-type sesterterpenoids, lendenfeldaranes W-Y (1-3), along with a known analogue, lendenfeldarane D (4), were isolated from a marine sponge identified as <i>Lendenfeldia</i> species. The structures of all isolates were determined based on spectroscopic methods. Scalarane 1 exhibited significant activity in enhancing alkaline phosphatase (ALP) activity.RSC advances44877-44882https://www.ebi.ac.uk/biostudies/studies/S-EPMC12624399biostudies-literatureLendenfeldaranes W-Y, new 24-homoscalaranes from a marine sponge <i>Lendenfeldia</i> species.PMC12624399Tsou LKZhang MMZheng LGTseng CCChen YYChen JJPeng BRLiu YWWu YJSung PJHuang CYWen ZHSu JHCheng YBLiaw CCfalseLendenfeldaranes W-Y, new 24-homoscalaranes from a marine sponge <i>Lendenfeldia</i> species.Three new scalarane-type sesterterpenoids, lendenfeldaranes W-Y (1-3), along with a known analogue, lendenfeldarane D (4), were isolated from a marine sponge identified as <i>Lendenfeldia</i> species. The structures of all isolates were determined based on spectroscopic methods. Scalarane 1 exhibited significant activity in enhancing alkaline phosphatase (ALP) activity.2025-01-01T00:00:00Z2025 Nov2026-06-05T19:19:51.831Z2026-05-20T03:13:54.354ZS-EPMC126243994126259710.1039/d5ra07083j