{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang Y"],"funding":["the General Program of the Natural Science Foundation of Guangxi in China","the Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response","the Self-funded Scientific Research Project by the Health Commission of Guangxi Zhuang Autonomous Region","the Guangxi Key Research and Development Project","The Outstanding Youth Fund of The Natural Science Foundation of Guangxi in China"],"pagination":["3974"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12625293"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Background</h4>HIV post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP) are effective yet underutilized HIV prevention modalities. This study aims to evaluate the awareness-to-use cascade for PEP and PrEP, and to examine the transition from PEP to PrEP among men who have sex with men (MSM). We will discuss the rationale for using PrEP after PEP use.<h4>Methods</h4>With an observational, longitudinal study design, MSM were recruited from five cities in Guangxi, China. Participants completed questionnaires every 3 months and were tracked for 12 months. Descriptive statistics summarized the awareness, use, cascade and transition of PEP and PrEP. The effect of PEP use on PrEP use was analyzed using Generalized Estimating Equations.<h4>Results</h4>A total of 363 eligible MSM "],"journal":["BMC public health"],"pubmed_title":["Transition from HIV post-exposure prophylaxis to pre-exposure prophylaxis and awareness-to-use cascade among men who have sex with men: a longitudinal study in Guangxi, China."],"pmcid":["PMC12625293"],"funding_grant_id":["Guike AB24010175","Z-A20240621","2023GXNSFFA026007","2023GXNSFAA026287","GKLKP-KF-202202"],"pubmed_authors":["Shi L","Ning C","Jiang L","Cen P","Huang H","Mo J","Wang H","Wang M","Zhu J","Huang Y","Tian W","Zhang Y","Tan S","Lan G"],"additional_accession":[]},"is_claimable":false,"name":"Transition from HIV post-exposure prophylaxis to pre-exposure prophylaxis and awareness-to-use cascade among men who have sex with men: a longitudinal study in Guangxi, China.","description":"<h4>Background</h4>HIV post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP) are effective yet underutilized HIV prevention modalities. This study aims to evaluate the awareness-to-use cascade for PEP and PrEP, and to examine the transition from PEP to PrEP among men who have sex with men (MSM). We will discuss the rationale for using PrEP after PEP use.<h4>Methods</h4>With an observational, longitudinal study design, MSM were recruited from five cities in Guangxi, China. Participants completed questionnaires every 3 months and were tracked for 12 months. Descriptive statistics summarized the awareness, use, cascade and transition of PEP and PrEP. The effect of PEP use on PrEP use was analyzed using Generalized Estimating Equations.<h4>Results</h4>A total of 363 eligible MSM ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T16:56:51.339Z","creation":"2026-06-05T03:06:55.208Z"},"accession":"S-EPMC12625293","cross_references":{"pubmed":["41250041"],"doi":["10.1186/s12889-025-25232-4"]}}