biostudies-literatureUnknown25(1)Sendra E<h4>Background</h4>Skin and soft tissue infections (SSTIs) cause an increasing demand for inpatient and outpatient medical care. In recent years, health systems have promoted strategies to treat selected patients on an outpatient basis, which may avoid hospital admissions and associated complications.<h4>Methods</h4>A retrospective, cohort study of adults presenting to the emergency department (ED) with a SSTI between 2018 and 2020.<h4>Primary objective</h4>to compare clinical outcomes in patients with SSTI treated as outpatients or inpatients.<h4>Primary outcome</h4>Early clinical failure.<h4>Secondary outcomes</h4>Recurrences, unplanned readmissions and ED visits related to the SSTI.<h4>Secondary objective</h4>to investigate factors associated with eligibility for early discharge of inpaBMC infectious diseases1594https://www.ebi.ac.uk/biostudies/studies/S-EPMC12625354biostudies-literatureInpatient versus outpatient management of community-acquired acute skin and soft tissue infections. Clinical outcomes and factors associated with eligibility for early discharge.PMC12625354Sanchez FPoblet-Florentin JVizoso-Exposito AHorcajada JPCastaneda SCanas-Ruano EAlanti SSDuran-Jorda XRodriguez-Alarcon AGonzalez-Castillo AMSabate REsteban-Cuco SGomez-Zorrilla SLopez-Montesinos ISendra EMembrilla-Fernandez ESuarez AfalseInpatient versus outpatient management of community-acquired acute skin and soft tissue infections. Clinical outcomes and factors associated with eligibility for early discharge.<h4>Background</h4>Skin and soft tissue infections (SSTIs) cause an increasing demand for inpatient and outpatient medical care. In recent years, health systems have promoted strategies to treat selected patients on an outpatient basis, which may avoid hospital admissions and associated complications.<h4>Methods</h4>A retrospective, cohort study of adults presenting to the emergency department (ED) with a SSTI between 2018 and 2020.<h4>Primary objective</h4>to compare clinical outcomes in patients with SSTI treated as outpatients or inpatients.<h4>Primary outcome</h4>Early clinical failure.<h4>Secondary outcomes</h4>Recurrences, unplanned readmissions and ED visits related to the SSTI.<h4>Secondary objective</h4>to investigate factors associated with eligibility for early discharge of inpa2025-01-01T00:00:00Z2025 Nov2026-06-05T19:22:57.118Z2026-05-20T03:14:19.035ZS-EPMC126253544124996610.1186/s12879-025-11883-6