biostudies-literatureBind RHWellcome Trust836-845https://www.ebi.ac.uk/biostudies/studies/S-EPMC12628126biostudies-literatureUnknown227(6)<h4>Background</h4>Postnatal depression (PND) affects up to one in four mothers. However, they may experience barriers to access to conventional treatments, indicating a need for alternatives such as arts-based interventions. A previous trial showed that a 10-week singing intervention could alleviate symptoms of PND.<h4>Aims</h4>To evaluate, in a larger sample and across a longer timeframe than previously, the clinical effectiveness, implementation effectiveness and cost-effectiveness of the Melodies for Mums (M4M) singing intervention for symptoms of PND.<h4>Method</h4>One-hundred and ninety-nine mothers experiencing symptoms of PND (Edinburgh Postnatal Depression Scale score ≥10) and their babies were randomised to 10 weeks of in-person singing sessions (M4M, <i>n</i> = 133) or an activeThe British journal of psychiatry : the journal of mental scienceClinical effectiveness, implementation effectiveness and cost-effectiveness of a community singing intervention for postnatal depressive symptoms, SHAPER-PND: randomised controlled trial.PMC12628126219425/Z/19/ZLopez MBLaijawala RFancourt DAgwuna JCrane NPerkins RPariante CMDavis RHazelgrove KHealey ADye HBurton ARebecchini LSevdalis NLawrence AJPriestley KEstevao CMiller CDazzan PBind RHBakolis IManoharan MOsborn TWoods AJGreenwood LfalseClinical effectiveness, implementation effectiveness and cost-effectiveness of a community singing intervention for postnatal depressive symptoms, SHAPER-PND: randomised controlled trial.<h4>Background</h4>Postnatal depression (PND) affects up to one in four mothers. However, they may experience barriers to access to conventional treatments, indicating a need for alternatives such as arts-based interventions. A previous trial showed that a 10-week singing intervention could alleviate symptoms of PND.<h4>Aims</h4>To evaluate, in a larger sample and across a longer timeframe than previously, the clinical effectiveness, implementation effectiveness and cost-effectiveness of the Melodies for Mums (M4M) singing intervention for symptoms of PND.<h4>Method</h4>One-hundred and ninety-nine mothers experiencing symptoms of PND (Edinburgh Postnatal Depression Scale score ≥10) and their babies were randomised to 10 weeks of in-person singing sessions (M4M, <i>n</i> = 133) or an active2025-01-01T00:00:00Z2025 Dec2026-06-06T06:29:47.11Z2026-06-06T03:06:19.375ZS-EPMC126281264108702010.1192/bjp.2025.10377