{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Wen Y"],"pubmed_abstract":["<h4>Background</h4>The prognostic significance of long non-coding RNA ST8SIA6-AS1 remains ambiguous, and its biological role in prostate cancer (PCa) has not been thoroughly investigated. This study seeks to conduct a comprehensive meta-analysis to assess the clinical relevance of ST8SIA6-AS1 across different malignancies, with a particular emphasis on elucidating its functions in the advancement of PCa.<h4>Methods</h4>Systematic searches were conducted in the PubMed, Embase, and Web of Science databases to select studies that met the criteria. Data, including hazard ratios (HR) with 95% confidence intervals (95% CI) and clinical pathological parameters, were collected. Subgroup analyses were performed based on sample size and tumor type. The expression profile analysis of PCa tissues was "],"journal":["Frontiers in genetics"],"pagination":["1648077"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12634032"],"repository":["biostudies-literature"],"pubmed_title":["ST8SIA6-AS1 serves as a prognostic biomarker in cancer and exhibits oncogenic properties in prostate cancer."],"pmcid":["PMC12634032"],"pubmed_authors":["Wen Y","Yang J","Huang Y","Zhan S","Chen G","Zheng S","Zhu S"],"additional_accession":[]},"is_claimable":false,"name":"ST8SIA6-AS1 serves as a prognostic biomarker in cancer and exhibits oncogenic properties in prostate cancer.","description":"<h4>Background</h4>The prognostic significance of long non-coding RNA ST8SIA6-AS1 remains ambiguous, and its biological role in prostate cancer (PCa) has not been thoroughly investigated. This study seeks to conduct a comprehensive meta-analysis to assess the clinical relevance of ST8SIA6-AS1 across different malignancies, with a particular emphasis on elucidating its functions in the advancement of PCa.<h4>Methods</h4>Systematic searches were conducted in the PubMed, Embase, and Web of Science databases to select studies that met the criteria. Data, including hazard ratios (HR) with 95% confidence intervals (95% CI) and clinical pathological parameters, were collected. Subgroup analyses were performed based on sample size and tumor type. The expression profile analysis of PCa tissues was ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-19T03:21:16.245Z","creation":"2026-05-19T03:11:49.661Z"},"accession":"S-EPMC12634032","cross_references":{"pubmed":["41282486"],"doi":["10.3389/fgene.2025.1648077"]}}