biostudies-literatureWang YNational Major Science and Technology Projects of China,China939https://www.ebi.ac.uk/biostudies/studies/S-EPMC12639971biostudies-literatureUnknown25(1)<h4>Background</h4>Post-induction hypotension (PIH) is a frequent complication among older adults undergoing general anaesthesia, associated with organ hypoperfusion and increased perioperative risk. The role of body mass index (BMI), a routinely assessed and potentially modifiable risk factor, in the development of PIH remains unclear in geriatric populations.<h4>Methods</h4>We conducted a retrospective cohort study of patients aged ≥ 60 years who underwent elective non-cardiac surgery under general anaesthesia between 2013 and 2022 at a tertiary hospital. Preoperative BMI was analysed both as a continuous and categorical variable. The primary outcome was PIH, defined as a systolic blood pressure < 90 mmHg or > 30% reduction from baseline during the post-induction period. Secondary outcomBMC geriatricsBody mass index and risk of post-induction hypotension in older adults undergoing non-cardiac surgery: a retrospective cohort study.PMC126399712023ZD0501801Shen LZhang YTian YLan LWang YXu XWang JfalseBody mass index and risk of post-induction hypotension in older adults undergoing non-cardiac surgery: a retrospective cohort study.<h4>Background</h4>Post-induction hypotension (PIH) is a frequent complication among older adults undergoing general anaesthesia, associated with organ hypoperfusion and increased perioperative risk. The role of body mass index (BMI), a routinely assessed and potentially modifiable risk factor, in the development of PIH remains unclear in geriatric populations.<h4>Methods</h4>We conducted a retrospective cohort study of patients aged ≥ 60 years who underwent elective non-cardiac surgery under general anaesthesia between 2013 and 2022 at a tertiary hospital. Preoperative BMI was analysed both as a continuous and categorical variable. The primary outcome was PIH, defined as a systolic blood pressure < 90 mmHg or > 30% reduction from baseline during the post-induction period. Secondary outcom2025-01-01T00:00:00Z2025 Nov2026-06-05T17:29:25.212Z2026-06-05T03:07:14.527ZS-EPMC126399714127250110.1186/s12877-025-06691-1