{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["60(10)"],"submitter":["Krajewski A"],"pubmed_abstract":["<h4>Aim</h4>The objective of this systematic review and meta-analysis was to evaluate the influence of non-surgical periodontal therapy (NSPT) on subgingival microbiota in systemically healthy patients with periodontitis.<h4>Methods</h4>A systematic literature search was conducted in Medline, Embase, LILACS, and the Cochrane Library, supplemented by a manual search for studies investigating the effect of NSPT on subgingival microbiota in systemically healthy patients.<h4>Results</h4>In this review, 115 studies were included, of which 41 used checkerboard DNA-DNA hybridisation technology, 30 real-time quantitative PCR, 36 bacterial culture, and 8 16S ribosomal ribonucleic acid (rRNA) gene sequencing technology. Meta-analyses showed a significant decrease in mean counts of Aggregatibacter ac"],"journal":["Journal of periodontal research"],"pagination":["963-993"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12640219"],"repository":["biostudies-literature"],"pubmed_title":["The Effect of Non-Surgical Periodontal Therapy on Subgingival Microbiota: A Systematic Review and Meta-Analysis."],"pmcid":["PMC12640219"],"pubmed_authors":["Ercal P","Donos N","Perussolo J","Gkranias N","Krajewski A"],"additional_accession":[]},"is_claimable":false,"name":"The Effect of Non-Surgical Periodontal Therapy on Subgingival Microbiota: A Systematic Review and Meta-Analysis.","description":"<h4>Aim</h4>The objective of this systematic review and meta-analysis was to evaluate the influence of non-surgical periodontal therapy (NSPT) on subgingival microbiota in systemically healthy patients with periodontitis.<h4>Methods</h4>A systematic literature search was conducted in Medline, Embase, LILACS, and the Cochrane Library, supplemented by a manual search for studies investigating the effect of NSPT on subgingival microbiota in systemically healthy patients.<h4>Results</h4>In this review, 115 studies were included, of which 41 used checkerboard DNA-DNA hybridisation technology, 30 real-time quantitative PCR, 36 bacterial culture, and 8 16S ribosomal ribonucleic acid (rRNA) gene sequencing technology. Meta-analyses showed a significant decrease in mean counts of Aggregatibacter ac","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T17:22:49.211Z","creation":"2026-05-19T03:12:04.882Z"},"accession":"S-EPMC12640219","cross_references":{"pubmed":["40347039"],"doi":["10.1111/jre.13409"]}}