{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Chen P"],"pubmed_abstract":["<h4>Purpose</h4>Accurate identification of computed tomography (CT) perfusion ischemic core in patients with basilar artery occlusion (BAO) on admission remains challenging despite its critical role in prognostic prediction and treatment decision-making. We aimed to define the optimal threshold for identifying the ischemic core by assessing agreement in lesion extent and spatial distribution using Syngo.via.<h4>Methods</h4>We retrospectively analyzed 91 patients with BAO who achieved successful recanalization after endovascular thrombectomy at our center. The ischemic core was estimated using the following thresholds: cerebral blood flow (CBF) < 10 or 15 mL/100 g/min by Syngo.via, cerebral blood volume < 1.2 mL/100 mL by Syngo.via, and time to maximum > 10 s by RAPID. The Posterior Circula"],"journal":["Frontiers in neurology"],"pagination":["1678450"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12641287"],"repository":["biostudies-literature"],"pubmed_title":["Accuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy."],"pmcid":["PMC12641287"],"pubmed_authors":["Chen P","Xia S","Ji J","Hui J","Ding Q","Zhang W","Li X","Gao R","Huang Y","Shang L","Rao J","Chen X","Zhou J"],"additional_accession":[]},"is_claimable":false,"name":"Accuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy.","description":"<h4>Purpose</h4>Accurate identification of computed tomography (CT) perfusion ischemic core in patients with basilar artery occlusion (BAO) on admission remains challenging despite its critical role in prognostic prediction and treatment decision-making. We aimed to define the optimal threshold for identifying the ischemic core by assessing agreement in lesion extent and spatial distribution using Syngo.via.<h4>Methods</h4>We retrospectively analyzed 91 patients with BAO who achieved successful recanalization after endovascular thrombectomy at our center. The ischemic core was estimated using the following thresholds: cerebral blood flow (CBF) < 10 or 15 mL/100 g/min by Syngo.via, cerebral blood volume < 1.2 mL/100 mL by Syngo.via, and time to maximum > 10 s by RAPID. The Posterior Circula","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-05T18:26:26.163Z","creation":"2026-05-20T03:12:02.938Z"},"accession":"S-EPMC12641287","cross_references":{"pubmed":["41293415"],"doi":["10.3389/fneur.2025.1678450"]}}