biostudies-literatureUnknown16Chen P<h4>Purpose</h4>Accurate identification of computed tomography (CT) perfusion ischemic core in patients with basilar artery occlusion (BAO) on admission remains challenging despite its critical role in prognostic prediction and treatment decision-making. We aimed to define the optimal threshold for identifying the ischemic core by assessing agreement in lesion extent and spatial distribution using Syngo.via.<h4>Methods</h4>We retrospectively analyzed 91 patients with BAO who achieved successful recanalization after endovascular thrombectomy at our center. The ischemic core was estimated using the following thresholds: cerebral blood flow (CBF) < 10 or 15 mL/100 g/min by Syngo.via, cerebral blood volume < 1.2 mL/100 mL by Syngo.via, and time to maximum > 10 s by RAPID. The Posterior CirculaFrontiers in neurology1678450https://www.ebi.ac.uk/biostudies/studies/S-EPMC12641287biostudies-literatureAccuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy.PMC12641287Chen PXia SJi JHui JDing QZhang WLi XGao RHuang YShang LRao JChen XZhou JfalseAccuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy.<h4>Purpose</h4>Accurate identification of computed tomography (CT) perfusion ischemic core in patients with basilar artery occlusion (BAO) on admission remains challenging despite its critical role in prognostic prediction and treatment decision-making. We aimed to define the optimal threshold for identifying the ischemic core by assessing agreement in lesion extent and spatial distribution using Syngo.via.<h4>Methods</h4>We retrospectively analyzed 91 patients with BAO who achieved successful recanalization after endovascular thrombectomy at our center. The ischemic core was estimated using the following thresholds: cerebral blood flow (CBF) < 10 or 15 mL/100 g/min by Syngo.via, cerebral blood volume < 1.2 mL/100 mL by Syngo.via, and time to maximum > 10 s by RAPID. The Posterior Circula2025-01-01T00:00:00Z20252026-06-05T18:26:26.163Z2026-05-20T03:12:02.938ZS-EPMC126412874129341510.3389/fneur.2025.1678450