{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(1)"],"submitter":["Chen C"],"pubmed_abstract":["Retrospective cues in working memory (WM) prioritize relevant information and guide attention toward target items to optimize behavior. Although the frontoparietal attention network is known to support this top-down attention mechanism, the broader cortical network behind this process remains elusive. Here, by combining EEG source localization with Bayesian non-negative matrix factorization, we identify nine WM task-related subnetworks, including two newly identified networks: the left parahippocampal-insula network (lPIN) and the right parahippocampal-insula network (rPIN). Dynamic network similarity (DNS) analysis reveals that the brain rapidly transitions into a 'silent' state following memory encoding. During retention, both retro- and neutral-cues reactivate memory representation; how"],"journal":["Communications biology"],"pagination":["1648"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12644547"],"repository":["biostudies-literature"],"pubmed_title":["Prioritizing flexible working memory representations relies on the involvement of the parahippocampal-insula network during memory reactivation."],"pmcid":["PMC12644547"],"pubmed_authors":["Xie Y","Li C","Xu P","Zhang X","Li F","Yao D","Xu S","Yi C","Chen C","Zhao J"],"additional_accession":[]},"is_claimable":false,"name":"Prioritizing flexible working memory representations relies on the involvement of the parahippocampal-insula network during memory reactivation.","description":"Retrospective cues in working memory (WM) prioritize relevant information and guide attention toward target items to optimize behavior. Although the frontoparietal attention network is known to support this top-down attention mechanism, the broader cortical network behind this process remains elusive. Here, by combining EEG source localization with Bayesian non-negative matrix factorization, we identify nine WM task-related subnetworks, including two newly identified networks: the left parahippocampal-insula network (lPIN) and the right parahippocampal-insula network (rPIN). Dynamic network similarity (DNS) analysis reveals that the brain rapidly transitions into a 'silent' state following memory encoding. During retention, both retro- and neutral-cues reactivate memory representation; how","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T19:01:13.301Z","creation":"2026-05-20T03:14:24.486Z"},"accession":"S-EPMC12644547","cross_references":{"pubmed":["41286355"],"doi":["10.1038/s42003-025-09029-0"]}}