{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Geng J"],"funding":["MEXT | Japan Society for the Promotion of Science (JSPS)","Natural Science Foundation of Shaanxi Province (Shaanxi Province Natural Science Foundation)","National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["10369"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12644751"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["Pure-organic semiconductors have attracted broad interest in tissue-equivalent and biocompatible X-ray sensors, while their low-dose X-ray imaging capability still suffers from poor charge transport properties. Here, we report a dimensionality tailoring method to enhance hole transport in pure-organic semiconductors, enabling highly stable and low-dose X-ray detection and imaging without toxic elements such as Pb or Hg. By substituting the -CN group in 4-hydroxycyanobenzene (4HCB, HO-C<sub>6</sub>H<sub>4</sub>-CN) with a -COOCH<sub>3</sub> group, we transform the two-dimensional (2D) structure into a three-dimensional (3D) 4-methyl hydroxybenzoate (4MHB, HO-C<sub>6</sub>H<sub>4</sub>-COOCH<sub>3</sub>) crystal featuring enhanced intermolecular π-π stacking. This structural reconfiguration "],"journal":["Nature communications"],"pubmed_title":["Dimensionality-tailored pure organic semiconductor with high hole mobility for low-dose x-ray imaging."],"pmcid":["PMC12644751"],"funding_grant_id":["Nos. 12435013","24KF0193","2024RS-CXTD-62","Nos. 62104194"],"pubmed_authors":["Peng X","Zhou L","Zheng Z","Xu M","Li C","Liu M","Zhang H","Geng J","Zheng W","Gao Z","Jie W","Zhao D","Ma D","Jia Z","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Dimensionality-tailored pure organic semiconductor with high hole mobility for low-dose x-ray imaging.","description":"Pure-organic semiconductors have attracted broad interest in tissue-equivalent and biocompatible X-ray sensors, while their low-dose X-ray imaging capability still suffers from poor charge transport properties. Here, we report a dimensionality tailoring method to enhance hole transport in pure-organic semiconductors, enabling highly stable and low-dose X-ray detection and imaging without toxic elements such as Pb or Hg. By substituting the -CN group in 4-hydroxycyanobenzene (4HCB, HO-C<sub>6</sub>H<sub>4</sub>-CN) with a -COOCH<sub>3</sub> group, we transform the two-dimensional (2D) structure into a three-dimensional (3D) 4-methyl hydroxybenzoate (4MHB, HO-C<sub>6</sub>H<sub>4</sub>-COOCH<sub>3</sub>) crystal featuring enhanced intermolecular π-π stacking. This structural reconfiguration ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T18:57:33.581Z","creation":"2026-05-20T03:14:15.181Z"},"accession":"S-EPMC12644751","cross_references":{"pubmed":["41285785"],"doi":["10.1038/s41467-025-65349-z"]}}