{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(11)"],"submitter":["Lowrie R"],"pubmed_abstract":["<h4>Introduction</h4>People experiencing severe and multiple disadvantage (SMD: homelessness, substance use and criminal offending) have multiple intersecting unmet health and social care needs and high mortality rates, often due to street-drug overdose. Pilot randomised controlled trials (RCTs) suggest an integrated, holistic, collaborative outreach intervention (Pharmacy Homeless Outreach Engagement Non-medical Independent Prescribing Rx (PHOENIx)) involving generalist-trained pharmacists, nurses or General Practitioners accompanied by staff from third sector homeless organisations may improve outcomes, including reducing overdose.<h4>Methods</h4>Multicentre, parallel group, prospective RCT with parallel economic and process evaluation. Set in six areas of Scotland, UK, 378 adults with S"],"journal":["BMJ open"],"pagination":["e106640"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12645644"],"repository":["biostudies-literature"],"pubmed_title":["Protocol for a multicentre randomised controlled trial of the Pharmacy Homeless Outreach Engagement Non-medical and Independent Prescriber (PHOENIx) intervention for people facing severe and multiple disadvantages."],"pmcid":["PMC12645644"],"pubmed_authors":["Vickery K","MacLean G","Kelly S","Williamson AE","McGilvery E","Adam A","Sutherland A","Rushworth G","Garstka Z","Melville L","Rowe A","Orr T","Thomson E","Maclean A","Breingan Z","Lilley J","Macaulay M","Paudyal V","Murphy J","Cortez MA","Marshall T","Dos Santos C","Raeburn F","Budd J","Stoddart A","Duncan G","Moir J","McKinney E","Lewis S","McPherson A","Kennedy H","Ali Akbar H","Nelson K","Johnsen S","Robertson C","Orr M","Carnegie J","O'Loan J","Rosinska M","Lowrie R","Esson K"],"additional_accession":[]},"is_claimable":false,"name":"Protocol for a multicentre randomised controlled trial of the Pharmacy Homeless Outreach Engagement Non-medical and Independent Prescriber (PHOENIx) intervention for people facing severe and multiple disadvantages.","description":"<h4>Introduction</h4>People experiencing severe and multiple disadvantage (SMD: homelessness, substance use and criminal offending) have multiple intersecting unmet health and social care needs and high mortality rates, often due to street-drug overdose. Pilot randomised controlled trials (RCTs) suggest an integrated, holistic, collaborative outreach intervention (Pharmacy Homeless Outreach Engagement Non-medical Independent Prescribing Rx (PHOENIx)) involving generalist-trained pharmacists, nurses or General Practitioners accompanied by staff from third sector homeless organisations may improve outcomes, including reducing overdose.<h4>Methods</h4>Multicentre, parallel group, prospective RCT with parallel economic and process evaluation. Set in six areas of Scotland, UK, 378 adults with S","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T19:01:23.321Z","creation":"2026-05-20T03:14:27.936Z"},"accession":"S-EPMC12645644","cross_references":{"pubmed":["41285500"],"doi":["10.1136/bmjopen-2025-106640"]}}