biostudies-literatureUnknown12Tang J<h4>Background</h4>Thoracic paravertebral block (TPVB) is a clinically valuable regional anesthesia and analgesia technique for managing postoperative acute pain and certain chronic pain conditions. There are several approaches for ultrasound-guided TPVB. However, currently it is hard to provide an evidence-based recommendation on the choice between approaches. Comparisons of injectate distribution patterns among different approaches are limited. This observational cadaveric study compared dye distribution following TPVB using transverse <i>in-plane</i> (TI) and sagittal <i>in-plane</i> (SI) ultrasound-guidance.<h4>Methods</h4>Ten paravertebral injections at the T6-7 were performed on five cadavers. Left side received injections with TI approach, and right side with SI approach. All injectFrontiers in medicine1667862https://www.ebi.ac.uk/biostudies/studies/S-EPMC12647097biostudies-literatureComparison of injectate spread following transverse vs. sagittal &lt;i&gt;in-plane&lt;/i&gt; ultrasound-guided thoracic paravertebral block: a cadaveric study.PMC12647097Tang JWang NBai BZhang DMa CHuang YMa MZhang YTang SShen XBi YfalseComparison of injectate spread following transverse vs. sagittal &lt;i&gt;in-plane&lt;/i&gt; ultrasound-guided thoracic paravertebral block: a cadaveric study.<h4>Background</h4>Thoracic paravertebral block (TPVB) is a clinically valuable regional anesthesia and analgesia technique for managing postoperative acute pain and certain chronic pain conditions. There are several approaches for ultrasound-guided TPVB. However, currently it is hard to provide an evidence-based recommendation on the choice between approaches. Comparisons of injectate distribution patterns among different approaches are limited. This observational cadaveric study compared dye distribution following TPVB using transverse <i>in-plane</i> (TI) and sagittal <i>in-plane</i> (SI) ultrasound-guidance.<h4>Methods</h4>Ten paravertebral injections at the T6-7 were performed on five cadavers. Left side received injections with TI approach, and right side with SI approach. All inject2025-01-01T00:00:00Z20252026-06-05T16:43:43.126Z2026-05-18T03:13:12.373ZS-EPMC126470974131245710.3389/fmed.2025.1667862