{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["82"],"submitter":["Zamora V"],"pubmed_abstract":["<h4>Background and objective</h4>Our objective was to compare the impact of open radical prostatectomy (RP), external beam radiotherapy (EBRT), and brachytherapy in patients with localized prostate cancer via patient-reported outcome measures up to 20 yr after treatment.<h4>Methods</h4>This was a prospective observational study (ClinicalTrials.gov NCT01492751) of men with localized prostate cancer (clinical stage T1-T2, low or intermediate risk). The Expanded Prostate Cancer Index Composite (EPIC-26) and Short Form-36 (SF-36) questionnaires were centrally administered via telephone interviews before treatment and then annually after treatment. Generalized estimating equation models were constructed with propensity score-based weights.<h4>Key findings and limitations</h4>The RP group report"],"journal":["European urology open science"],"pagination":["160-167"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12648591"],"repository":["biostudies-literature"],"pubmed_title":["Twenty-year Patient-reported Outcomes After Surgery, Radiotherapy, or Brachytherapy for Localized Prostate Cancer."],"pmcid":["PMC12648591"],"pubmed_authors":["Ventura M","Sancho G","Bonet X","Alonso J","de Paula B","Ortiz MJ","Suarez JF","Goni A","Garin O","Ferrer F","Pont A","Palou J","Herruzo I","de Leon JP","Guedea F","Cabrera P","Avila M","Macias V","Fernandez P","Ferrer M","Ponce de Leon J","Castells M","Pastor S","Gutierrez C","Pardo Y","Hervas A","Multicenter Spanish Group for Clinically Localized Prostate Cancer","Sole J","Bonet C","Marino A","Zamora V","Boladeras A","Ramos A","Bonet M"],"additional_accession":[]},"is_claimable":false,"name":"Twenty-year Patient-reported Outcomes After Surgery, Radiotherapy, or Brachytherapy for Localized Prostate Cancer.","description":"<h4>Background and objective</h4>Our objective was to compare the impact of open radical prostatectomy (RP), external beam radiotherapy (EBRT), and brachytherapy in patients with localized prostate cancer via patient-reported outcome measures up to 20 yr after treatment.<h4>Methods</h4>This was a prospective observational study (ClinicalTrials.gov NCT01492751) of men with localized prostate cancer (clinical stage T1-T2, low or intermediate risk). The Expanded Prostate Cancer Index Composite (EPIC-26) and Short Form-36 (SF-36) questionnaires were centrally administered via telephone interviews before treatment and then annually after treatment. Generalized estimating equation models were constructed with propensity score-based weights.<h4>Key findings and limitations</h4>The RP group report","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-05T18:46:38.891Z","creation":"2026-05-20T03:13:22.796Z"},"accession":"S-EPMC12648591","cross_references":{"pubmed":["41311640"],"doi":["10.1016/j.euros.2025.10.007"]}}