{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Adero J"],"funding":["The Genomic Tools for Sweetpotato Improvement (GT4SP) project funded by the BMGF provided additional funds for the research"],"pagination":["1541"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12650080"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(11)"],"pubmed_abstract":["Sweetpotato (<i>Ipomoea batatas</i> L. Lam) production is threatened by complex viral diseases, notably sweet potato virus disease (SPVD) worldwide, which results from co-infection by <i>sweet potato feathery mottle virus</i> (SPFMV) and <i>sweet potato chlorotic stunt virus</i> (SPCSV). This study provides virus-specific transcriptomic insights into the immune responses of three sweetpotato cultivars, 'Beauregard', 'Tanzania', and 'New Kawogo', to SPFMV, SPCSV, and SPVD. Using RNA-seq profiling across three timepoints post-infection at 3, 6, and 12 weeks, we identified distinct virus- and genotype-specific gene expression responses. 'New Kawogo' activated early and sustained immune pathways involving redox regulation, transcriptional control, and hormonal signaling in response to both SPC"],"journal":["Biology"],"pubmed_title":["Virus-Specific Defense Responses in Sweetpotato: Transcriptomic Insights into Resistance and Susceptibility to SPFMV, SPCSV, and SPVD."],"pmcid":["PMC12650080"],"funding_grant_id":["Contract ID: OPP1052983"],"pubmed_authors":["Aber PP","Opiyo SO","Yada B","Dube F","Segundo F","Byarugaba DK","Adero J","Maria D","Ssali R","Kitavi M","Fei Z","Kreuze JF"],"additional_accession":[]},"is_claimable":false,"name":"Virus-Specific Defense Responses in Sweetpotato: Transcriptomic Insights into Resistance and Susceptibility to SPFMV, SPCSV, and SPVD.","description":"Sweetpotato (<i>Ipomoea batatas</i> L. Lam) production is threatened by complex viral diseases, notably sweet potato virus disease (SPVD) worldwide, which results from co-infection by <i>sweet potato feathery mottle virus</i> (SPFMV) and <i>sweet potato chlorotic stunt virus</i> (SPCSV). This study provides virus-specific transcriptomic insights into the immune responses of three sweetpotato cultivars, 'Beauregard', 'Tanzania', and 'New Kawogo', to SPFMV, SPCSV, and SPVD. Using RNA-seq profiling across three timepoints post-infection at 3, 6, and 12 weeks, we identified distinct virus- and genotype-specific gene expression responses. 'New Kawogo' activated early and sustained immune pathways involving redox regulation, transcriptional control, and hormonal signaling in response to both SPC","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-19T03:27:32.101Z","creation":"2026-05-19T03:12:23.836Z"},"accession":"S-EPMC12650080","cross_references":{"pubmed":["41300334"],"doi":["10.3390/biology14111541"]}}