biostudies-literatureTsui TCOCanadian Partnership Against Cancer Corporation and Health CanadaSunnybrook Alternative Funding Plan AssociationEuroQol Research Foundation645https://www.ebi.ac.uk/biostudies/studies/S-EPMC12651012biostudies-literatureUnknown32(11)<h4>Background</h4>EQ-5D-3L health utilities inform health technology assessments in oncology, often derived from clinical trials enrolling highly selected populations, which may over-estimate real-world health utilities. Little is known about the association between socioeconomic status (SES) and EQ-5D-3L health utilities. Our objective was to examine EQ-5D-3L health utilities across SES in a real-world sample of patients with cancer.<h4>Methods</h4>We conducted a cross-sectional analysis of EQ-5D-3L responses from 170 adult patients with cancer accrued from an Ontario oncology centre. We fitted multivariable linear regression models to estimate associations between covariates and EQ-5D-3L health utilities.<h4>Results</h4>Lower EQ-5D-3L health utilities were significantly associated with the lowest and undisclosed family income categories in models with and without birth sex (<i>p</i> < 0.05). In the model including birth sex, disutility estimates for lowest family income (<CAD 29K) and undisclosed income was -0.202, 95% CI (-0.371 to -0.033), and -0.123 (-0.235 to -0.012), respectively. For the model excluding birth sex, disutility estimates for lowest income and undisclosed income was -0.163 (-0.280 to -0.046) and -0.106 (-0.184 to -0.028).<h4>Conclusions</h4>Lower EQ-5D-3L health utilities were significantly associated with low income and nondisclosure, highlighting the need to incorporate SES in analyzing health utilities in cancer care.Current oncology (Toronto, Ont.)Examining the Association Between Equity-Related Factors and EQ-5D-3L Health Utilities of Patients with Cancer.PMC12651012#1456-PD#SHS-20-020#13283Chan KKWMercer RETsui TCOPullenayegum EMfalseExamining the Association Between Equity-Related Factors and EQ-5D-3L Health Utilities of Patients with Cancer.<h4>Background</h4>EQ-5D-3L health utilities inform health technology assessments in oncology, often derived from clinical trials enrolling highly selected populations, which may over-estimate real-world health utilities. Little is known about the association between socioeconomic status (SES) and EQ-5D-3L health utilities. Our objective was to examine EQ-5D-3L health utilities across SES in a real-world sample of patients with cancer.<h4>Methods</h4>We conducted a cross-sectional analysis of EQ-5D-3L responses from 170 adult patients with cancer accrued from an Ontario oncology centre. We fitted multivariable linear regression models to estimate associations between covariates and EQ-5D-3L health utilities.<h4>Results</h4>Lower EQ-5D-3L health utilities were significantly associated with the lowest and undisclosed family income categories in models with and without birth sex (<i>p</i> < 0.05). In the model including birth sex, disutility estimates for lowest family income (<CAD 29K) and undisclosed income was -0.202, 95% CI (-0.371 to -0.033), and -0.123 (-0.235 to -0.012), respectively. For the model excluding birth sex, disutility estimates for lowest income and undisclosed income was -0.163 (-0.280 to -0.046) and -0.106 (-0.184 to -0.028).<h4>Conclusions</h4>Lower EQ-5D-3L health utilities were significantly associated with low income and nondisclosure, highlighting the need to incorporate SES in analyzing health utilities in cancer care.2025-01-01T00:00:00Z2025 Nov2026-05-20T03:18:26.559Z2026-05-20T03:13:12.484ZS-EPMC126510124129470710.3390/curroncol32110645