{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yu X"],"funding":["the \"Xinglin Scholar\" Scientific Research Talent Training Program of Chengdu University of Traditional Chinese Medicine","the National Natural Science Foundation of China"],"pagination":["1376"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12652254"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(11)"],"pubmed_abstract":["<h4>Background</h4>Safflower (<i>Carthamus tinctorius</i> L.) is a multipurpose crop with both medicinal and economic values. Flavonoid glycosides are the core bioactive components of this species for preventing and treating cardiovascular and cerebrovascular diseases, yet their specific regulatory mechanisms remain insufficiently systematically elucidated.<h4>Methods</h4>Based on the whole-genome data of <i>Carthamus tinctorius</i> L., key MYB transcription factors regulating the flavonoid glycoside biosynthesis pathway in safflower were screened and verified via MeJA treatment.<h4>Results</h4>A total of 202 MYB transcription factors were identified, and 18 candidate genes were screened out. Further analysis showed that four genes (HH_019113, HH_009268, HH_009443 and HH_029380) were extre"],"journal":["Genes"],"pubmed_title":["Genome-Wide Screening for MYB Transcription Factors Involved in Flavonoid Glycoside Biosynthesis in &lt;i&gt;Carthamus tinctorius&lt;/i&gt; L."],"pmcid":["PMC12652254"],"funding_grant_id":["No. 82274039","Nos: QJJJ2023010, QJRC2021011"],"pubmed_authors":["Li Y","Hu Y","Zhang J","Chen J","Peng L","Yu X","Xian B","Wu X"],"additional_accession":[]},"is_claimable":false,"name":"Genome-Wide Screening for MYB Transcription Factors Involved in Flavonoid Glycoside Biosynthesis in &lt;i&gt;Carthamus tinctorius&lt;/i&gt; L.","description":"<h4>Background</h4>Safflower (<i>Carthamus tinctorius</i> L.) is a multipurpose crop with both medicinal and economic values. Flavonoid glycosides are the core bioactive components of this species for preventing and treating cardiovascular and cerebrovascular diseases, yet their specific regulatory mechanisms remain insufficiently systematically elucidated.<h4>Methods</h4>Based on the whole-genome data of <i>Carthamus tinctorius</i> L., key MYB transcription factors regulating the flavonoid glycoside biosynthesis pathway in safflower were screened and verified via MeJA treatment.<h4>Results</h4>A total of 202 MYB transcription factors were identified, and 18 candidate genes were screened out. Further analysis showed that four genes (HH_019113, HH_009268, HH_009443 and HH_029380) were extre","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-19T03:20:28.771Z","creation":"2026-05-19T03:11:46.105Z"},"accession":"S-EPMC12652254","cross_references":{"pubmed":["41300828"],"doi":["10.3390/genes16111376"]}}