{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(11)"],"submitter":["Hua Z"],"pubmed_abstract":["<h4>Background</h4>Thyroid hormone sensitivity has emerged as a critical factor in various diseases. However, its relationship with ischemic stroke-associated pneumonia (iSAP) in euthyroid patients with ischemic stroke remains poorly understood. This study aims to elucidate the association between thyroid hormone sensitivity indices and iSAP risk.<h4>Methods</h4>A total of 1,767 euthyroid patients with ischemic stroke were enrolled and categorized into the iSAP group (n = 376) and the non-iSAP group (n = 1,391). Univariate and multivariate logistic regression analyses were performed to assess the association between thyroid hormone sensitivity indices-including free triiodothyronine (FT3), free thyroxine (FT4), FT3/FT4 ratio, thyroid-stimulating hormone index (TSHI), Thyrotroph T4 Resistan"],"journal":["PloS one"],"pagination":["e0333057"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12654940"],"repository":["biostudies-literature"],"pubmed_title":["Association between thyroid hormone sensitivity and ischemic stroke-associated pneumonia: The role of FT3/FT4 ratio."],"pmcid":["PMC12654940"],"pubmed_authors":["Hua Z","Zhang Y","Rao Z","Zhu C"],"additional_accession":[]},"is_claimable":false,"name":"Association between thyroid hormone sensitivity and ischemic stroke-associated pneumonia: The role of FT3/FT4 ratio.","description":"<h4>Background</h4>Thyroid hormone sensitivity has emerged as a critical factor in various diseases. However, its relationship with ischemic stroke-associated pneumonia (iSAP) in euthyroid patients with ischemic stroke remains poorly understood. This study aims to elucidate the association between thyroid hormone sensitivity indices and iSAP risk.<h4>Methods</h4>A total of 1,767 euthyroid patients with ischemic stroke were enrolled and categorized into the iSAP group (n = 376) and the non-iSAP group (n = 1,391). Univariate and multivariate logistic regression analyses were performed to assess the association between thyroid hormone sensitivity indices-including free triiodothyronine (FT3), free thyroxine (FT4), FT3/FT4 ratio, thyroid-stimulating hormone index (TSHI), Thyrotroph T4 Resistan","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-05T17:57:12.192Z","creation":"2026-05-19T03:11:58.124Z"},"accession":"S-EPMC12654940","cross_references":{"pubmed":["41296678"],"doi":["10.1371/journal.pone.0333057"]}}