biostudies-literatureZhang YOpen Fund Project of Guangdong Provincial Key Laboratory of Environmental Catalysis and Health Risk ControlNational Natural Science Foundation of ChinaGuangxi Key Laboratory of environmental pollution control theory and technology987https://www.ebi.ac.uk/biostudies/studies/S-EPMC12656290biostudies-literatureUnknown13(11)Decabromodiphenyl ether (BDE209) has been widely used because of its excellent flame-retardant properties and ability. On the one hand, many studies have shown that the presence of BDE209 can potentially threaten human health and the environment. The production and processing of products containing BDE209 is prohibited except for special applications in China. On the other hand, the study of BDE209 on respiratory cells is not yet fully understood. Consequently, this study aims to investigate the mechanisms of toxic damage and oxidative stress induced by BDE209 exposure in lung epithelial Beas-2B cells. The proliferation of Beas-2B cells under BDE209 exposure was first analyzed by using a real-time label-free cell analyzer (RTCA). Then the cells' morphological changes were observed using laToxicsEffects of Decabromodiphenyl Ether (BDE209) Exposure on Toxicity and Oxidative Stress of Beas-2B Cells.PMC12656290Guike Neng 2101Z014GKLECHRC-03Guike Neng 2101Z01742207498Li GMao PZhang YXiao ZMa YFu MYang FXian BfalseEffects of Decabromodiphenyl Ether (BDE209) Exposure on Toxicity and Oxidative Stress of Beas-2B Cells.Decabromodiphenyl ether (BDE209) has been widely used because of its excellent flame-retardant properties and ability. On the one hand, many studies have shown that the presence of BDE209 can potentially threaten human health and the environment. The production and processing of products containing BDE209 is prohibited except for special applications in China. On the other hand, the study of BDE209 on respiratory cells is not yet fully understood. Consequently, this study aims to investigate the mechanisms of toxic damage and oxidative stress induced by BDE209 exposure in lung epithelial Beas-2B cells. The proliferation of Beas-2B cells under BDE209 exposure was first analyzed by using a real-time label-free cell analyzer (RTCA). Then the cells' morphological changes were observed using la2025-01-01T00:00:00Z2025 Nov2026-05-19T03:14:29.128Z2026-05-19T03:11:13.17ZS-EPMC126562904130453910.3390/toxics13110987