biostudies-literatureHitchon CAPublic Health Agency of Canada- COVID-19 Immunity Task Force.1130https://www.ebi.ac.uk/biostudies/studies/S-EPMC12656540biostudies-literatureUnknown13(11)<h4>Background</h4>Vaccination reduces Coronavirus disease-19 (COVID-19) infection severity. We evaluated COVID-19 vaccine uptake and effectiveness in people with immune mediated inflammatory diseases (pIMIDs) versus the general population.<h4>Methods</h4>Using population-based administrative health records, we identified cohorts between 2004 and 2022 with an IMID (rheumatoid arthritis <i>n</i> = 10,405, systemic autoimmune rheumatic disease <i>n</i> = 5888, inflammatory bowel disease <i>n</i> = 7911, multiple sclerosis <i>n</i> = 3665, psoriasis <i>n</i> = 23,948) who were matched (1:5) by age, sex, and region to general population comparators (<i>n</i> = 243,490) without these IMIDs. Between 1 January 2021 and 31 March 2022, rates of COVID-19 vaccine administration, hospitalizations withVaccinesCOVID-19 Vaccination, Hospitalization Rates, and Mortality Differ Between People with Diagnosed Immune Mediated Inflammatory Disease and the General Population: A Population-Based Study.PMC126565402122-HQ-000070Widdifield JBernstein CNMarrie RAHitchon CATaylor CPeschken CAKaplan GGLacaille DfalseCOVID-19 Vaccination, Hospitalization Rates, and Mortality Differ Between People with Diagnosed Immune Mediated Inflammatory Disease and the General Population: A Population-Based Study.<h4>Background</h4>Vaccination reduces Coronavirus disease-19 (COVID-19) infection severity. We evaluated COVID-19 vaccine uptake and effectiveness in people with immune mediated inflammatory diseases (pIMIDs) versus the general population.<h4>Methods</h4>Using population-based administrative health records, we identified cohorts between 2004 and 2022 with an IMID (rheumatoid arthritis <i>n</i> = 10,405, systemic autoimmune rheumatic disease <i>n</i> = 5888, inflammatory bowel disease <i>n</i> = 7911, multiple sclerosis <i>n</i> = 3665, psoriasis <i>n</i> = 23,948) who were matched (1:5) by age, sex, and region to general population comparators (<i>n</i> = 243,490) without these IMIDs. Between 1 January 2021 and 31 March 2022, rates of COVID-19 vaccine administration, hospitalizations with2025-01-01T00:00:00Z2025 Nov2026-05-19T03:21:50.687Z2026-05-19T03:11:55.606ZS-EPMC126565404129550410.3390/vaccines13111130