{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(3)"],"submitter":["Baker SJC"],"pubmed_abstract":["<h4>Background</h4><i>Clostridioides difficile</i> is a bacillus that can colonize the intestinal tract. <i>C. difficile</i> infection (CDI) is a common, health care-associated disease often coinciding with antibiotic use, with presentation ranging from diarrhea to toxic megacolon and death. However, individuals can carry the pathogen without exhibiting symptoms of disease. <i>C. difficile</i> carriers may serve as an important reservoir for in-hospital transmission of <i>C. difficile.</i> The objective of this study was to assess the role asymptomatic <i>C. difficile</i> carriers may play in pathogen transmission.<h4>Methods</h4>In this retrospective cohort study, rectal swabs collected to test for antimicrobial-resistant organisms either upon admission or during the hospital stay were us"],"journal":["Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada"],"pagination":["228-238"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12657012"],"repository":["biostudies-literature"],"pubmed_title":["Investigating in-hospital transmission of &lt;i&gt;Clostridioides difficile&lt;/i&gt; from asymptomatic patients."],"pmcid":["PMC12657012"],"pubmed_authors":["Usuanlele MT","Mertz D","Bulir D","Baker SJC","Loeb M","Maciejewski J","McArthur AG","Smieja M","Surette MG","Gilchrist J","Sharma DR"],"additional_accession":[]},"is_claimable":false,"name":"Investigating in-hospital transmission of &lt;i&gt;Clostridioides difficile&lt;/i&gt; from asymptomatic patients.","description":"<h4>Background</h4><i>Clostridioides difficile</i> is a bacillus that can colonize the intestinal tract. <i>C. difficile</i> infection (CDI) is a common, health care-associated disease often coinciding with antibiotic use, with presentation ranging from diarrhea to toxic megacolon and death. However, individuals can carry the pathogen without exhibiting symptoms of disease. <i>C. difficile</i> carriers may serve as an important reservoir for in-hospital transmission of <i>C. difficile.</i> The objective of this study was to assess the role asymptomatic <i>C. difficile</i> carriers may play in pathogen transmission.<h4>Methods</h4>In this retrospective cohort study, rectal swabs collected to test for antimicrobial-resistant organisms either upon admission or during the hospital stay were us","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-05T17:52:31.083Z","creation":"2026-05-19T03:11:04.179Z"},"accession":"S-EPMC12657012","cross_references":{"pubmed":["41311617"],"doi":["10.3138/jammi-2024-0041"]}}