biostudies-literatureApap Mangion SRosetrees TrustMultiple Sclerosis Society - UKNational Multiple Sclerosis Society - USNational Institute for Health and Care Researche71101https://www.ebi.ac.uk/biostudies/studies/S-EPMC12657254biostudies-literatureUnknown15(12)<h4>Background</h4>People with progressive multiple sclerosis (pwPMS), who typically have established lower limb dysfunction, experience greater disability from upper limb dysfunction (ULD). The 9-hole peg test (9HPT) is the primary clinical measure for ULD but does not fully capture the patient experience. The ABILHAND-23 is a well-validated patient-reported outcome measure (PROM) that evaluates bimanual ability in daily function. However, no large-scale studies have assessed if the 9HPT reflects the individual ULD experience in pwPMS.<h4>Objectives</h4>We sought to (van Munster et al. 2023) assess the associations between the ABILHAND-23 and 9HPT, and (Huertas-Hoyas et al. 2020) to assess the ability of the 9HPT and other relevant covariables to predict ABILHAND-23 scores, using baselineBrain and behaviorThe ABILHAND-23 Patient Reported Outcome Measure in Secondary Progressive Multiple Sclerosis: A Cross-Sectional Analysis With the Nine Hole Peg Test.PMC12657254HTA Project: 15/57/143Nicholas JBianchi AFarrell RLeibowitz MBraisher MFavarato GOraluzume OJohn NWright SApap Mangion SBlackstone JAngelis FVecchio GCalvi AWade CWilliams TUCL MS‐STAT2 InvestigatorsChataway JDoshi AfalseThe ABILHAND-23 Patient Reported Outcome Measure in Secondary Progressive Multiple Sclerosis: A Cross-Sectional Analysis With the Nine Hole Peg Test.<h4>Background</h4>People with progressive multiple sclerosis (pwPMS), who typically have established lower limb dysfunction, experience greater disability from upper limb dysfunction (ULD). The 9-hole peg test (9HPT) is the primary clinical measure for ULD but does not fully capture the patient experience. The ABILHAND-23 is a well-validated patient-reported outcome measure (PROM) that evaluates bimanual ability in daily function. However, no large-scale studies have assessed if the 9HPT reflects the individual ULD experience in pwPMS.<h4>Objectives</h4>We sought to (van Munster et al. 2023) assess the associations between the ABILHAND-23 and 9HPT, and (Huertas-Hoyas et al. 2020) to assess the ability of the 9HPT and other relevant covariables to predict ABILHAND-23 scores, using baseline2025-01-01T00:00:00Z2025 Dec2026-06-05T19:55:04.191Z2026-05-21T03:11:46.823ZS-EPMC126572544129987810.1002/brb3.71101