biostudies-literatureVyas KJBill and Melinda Gates Foundation698-710https://www.ebi.ac.uk/biostudies/studies/S-EPMC12658314biostudies-literatureUnknown39(8)<h4>Background</h4>Studies of child mortality that employ minimally invasive tissue sampling (MITS) produce highly accurate cause of death data; however, selection bias may render these as non-representative of their underlying populations.<h4>Objectives</h4>Estimate cause-specific mortality fractions and rates for the five most frequent causes-underlying and others in the chain of events leading to death-among stillbirths, neonatal, infant and child deaths-in Sub-Saharan Africa and South Asia, adjusted for any identified selection biases.<h4>Methods</h4>The Child Health and Mortality Prevention Surveillance (CHAMPS) Network collects standardised, population-based, longitudinal data on causes of death among stillbirths and under-five children in 12 catchments in seven countries in Sub-SahaPaediatric and perinatal epidemiologyMajor Causes of Perinatal and Paediatric Mortality in Sub-Saharan Africa and South Asia: Adjustment for Selection Bias in the CHAMPS Network.PMC12658314OPP1126780Xerinda EBassey IASolomon FSanogo DOrlien SMSDufera TManhique ZChitungo DSorour GNhampossa TAhmed DTennant SMNhacolo AAkelo VGarel MFlora MSAlkis-Ramirez RGary JKotloff KLMuir JARevathi GKowuor DWaller JLHossain MZLeulseged HBassat QMarami DMahtab SSalzberg NTMonjane CAlam MCHAMPS NetworkMutevedzi PMachemedza TCain CJFayorsey RKosia BLemma EChowdhury AIAol GVerani JRChawana RMadhi SBelachew ASwart PJVyas KJShirin TMunisul Islam KPhilipsborn RPNhachungue SMadewell ZJTasnim SMitei PKMaixenchs MDludlu NMocumbi SLuke RSquire JSMenendez CChowdhury MAIScott JAGSissoko SGetnet FMehta ADuduyemi BKeita AMGure THoque MLee KHIbrahim AMAhmed ASMNUNyamthimba PAcham YCarrilho CRitter JMWhitney CGNtuli CLala SGWise AGizaw MAHale MIgunza AMekonnen AFairchild KDSesay FRahman AJohnson JKTraore AKindcardett MMandomando IKourouma NKoplan JPBari SAsefa YAMunguambe KWinchell JMTesfaye TSidibe DRahman MMurila FOgbuanu IGurley ESFernandes FAdam YBegum FWale HOrdi JVelaphi SIslam FZaman KPratt SBramugy JWitherbee JAlemu AIslam KMArifeen SEOele ELiu LMoseray AKoka RValente MPetersen KGreene CLOundo JONair STapia MDWadula JSow SOKone DRakislova NAssefa NParveen SMadrid LEdris YSamura SHurtado JCAbdullahi YYSacoor CFritz AFentaw SOnyango DChawla KKamal MMosiur MTemesgen FRogena EArjuman FAhmed MSZaki SRDewey BGupta PMOnwuchekwa UUTippett-Barr BABlau DMKhan IAKuria MLombaard HYeshi MMfalseMajor Causes of Perinatal and Paediatric Mortality in Sub-Saharan Africa and South Asia: Adjustment for Selection Bias in the CHAMPS Network.<h4>Background</h4>Studies of child mortality that employ minimally invasive tissue sampling (MITS) produce highly accurate cause of death data; however, selection bias may render these as non-representative of their underlying populations.<h4>Objectives</h4>Estimate cause-specific mortality fractions and rates for the five most frequent causes-underlying and others in the chain of events leading to death-among stillbirths, neonatal, infant and child deaths-in Sub-Saharan Africa and South Asia, adjusted for any identified selection biases.<h4>Methods</h4>The Child Health and Mortality Prevention Surveillance (CHAMPS) Network collects standardised, population-based, longitudinal data on causes of death among stillbirths and under-five children in 12 catchments in seven countries in Sub-Saha2025-01-01T00:00:00Z2025 Nov2026-05-21T03:19:37.481Z2026-05-21T03:12:57.236ZS-EPMC126583144090526310.1111/ppe.70067