{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li Y"],"funding":["Wellcome Trust"],"pagination":["645"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12659045"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>Previous studies have reported inverse associations between total (poly)phenol intake or specific subclasses of (poly)phenols, estimated from dietary questionnaires, and cardiovascular disease (CVD) risk. However, no studies have examined (poly)phenol-rich dietary patterns and their corresponding urinary metabolite profiles in relation to CVD risk. This study investigated the associations between a (poly)phenol-rich dietary score (PPS-D), its urinary metabolic signature (PPS-M), and longitudinal CVD risk in the TwinsUK cohort.<h4>Methods</h4>We included 3110 participants (followed up for 11.20 ± 7.03 years) from TwinsUK who completed the EPIC-Norfolk Food Frequency Questionnaire with longitudinal data. A subset of 200 participants provided spot urine samples, in which 11"],"journal":["BMC medicine"],"pubmed_title":["Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort."],"pmcid":["PMC12659045"],"funding_grant_id":["212904/Z/18/Z"],"pubmed_authors":["Gibson R","Li Y","Pope R","Small KS","Spector TD","Rodriguez-Mateos A","Steves CJ","Yan X","Falchi M","Menni C","Xu Y","Bell JT"],"additional_accession":[]},"is_claimable":false,"name":"Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort.","description":"<h4>Background</h4>Previous studies have reported inverse associations between total (poly)phenol intake or specific subclasses of (poly)phenols, estimated from dietary questionnaires, and cardiovascular disease (CVD) risk. However, no studies have examined (poly)phenol-rich dietary patterns and their corresponding urinary metabolite profiles in relation to CVD risk. This study investigated the associations between a (poly)phenol-rich dietary score (PPS-D), its urinary metabolic signature (PPS-M), and longitudinal CVD risk in the TwinsUK cohort.<h4>Methods</h4>We included 3110 participants (followed up for 11.20 ± 7.03 years) from TwinsUK who completed the EPIC-Norfolk Food Frequency Questionnaire with longitudinal data. A subset of 200 participants provided spot urine samples, in which 11","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T21:31:31.024Z","creation":"2026-05-22T03:10:29.286Z"},"accession":"S-EPMC12659045","cross_references":{"pubmed":["41299455"],"doi":["10.1186/s12916-025-04481-5"]}}