{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["104(12)"],"submitter":["Long Y"],"pubmed_abstract":["To reveal the molecular regulatory differences in physiological adaptations of pigeons with different breeding objectives, this study compared the transcriptomic differences in the hearts and cerebellar vermis of homing pigeons (HP) and meat pigeons (MP). Phenotypic analysis showed that the heart index of HP was significantly higher than that of MP, which helps enhance functions such as blood circulation, supporting the metabolic demands for long-duration activity. However, no significant differences were observed in the cerebellar vermis indices. Transcriptomic analysis identified 162 differentially expressed genes (DEGs) in the heart and 192 in the cerebellar vermis. Differential genes in the heart were primarily enriched in pathways related to circulatory system processes, ventricle dev"],"journal":["Poultry science"],"pagination":["106071"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12664028"],"repository":["biostudies-literature"],"pubmed_title":["Transcriptomic insights into the heart and cerebellar vermis of pigeons: Breed-specific differences driven by selective breeding."],"pmcid":["PMC12664028"],"pubmed_authors":["Zhao L","Long Y","Zhang X","Long K","Ye G","Yang Q","Wang X","Chen D","Tang H"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic insights into the heart and cerebellar vermis of pigeons: Breed-specific differences driven by selective breeding.","description":"To reveal the molecular regulatory differences in physiological adaptations of pigeons with different breeding objectives, this study compared the transcriptomic differences in the hearts and cerebellar vermis of homing pigeons (HP) and meat pigeons (MP). Phenotypic analysis showed that the heart index of HP was significantly higher than that of MP, which helps enhance functions such as blood circulation, supporting the metabolic demands for long-duration activity. However, no significant differences were observed in the cerebellar vermis indices. Transcriptomic analysis identified 162 differentially expressed genes (DEGs) in the heart and 192 in the cerebellar vermis. Differential genes in the heart were primarily enriched in pathways related to circulatory system processes, ventricle dev","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-05-21T03:18:53.437Z","creation":"2026-05-21T03:12:58.505Z"},"accession":"S-EPMC12664028","cross_references":{"pubmed":["41240701"],"doi":["10.1016/j.psj.2025.106071"]}}