biostudies-literatureUnknown25(1)Pamukcu Gunaydın G<h4>Background</h4>Patients presenting to the ED with headache are placed in a quiet, darkened room to minimize external stimuli; however, creating and maintaining such an environment can be challenging in the context of a busy ED setting. This study evaluated whether adding noise-reduction earmuffs and sleep eye masks to standard metoclopramide therapy improves pain relief in adult patients presenting with acute primary headache in the emergency department.<h4>Methods</h4>This single-center, open-label, randomized, controlled, parallel-group trial was conducted in the urban emergency department of a tertiary care hospital. Adult patients diagnosed with primary headache were randomized (1:1:1:1) to receive: Standard treatment alone (10 mg metoclopramide in 150 mL normal saline over 10 min)BMC emergency medicine249https://www.ebi.ac.uk/biostudies/studies/S-EPMC12664183biostudies-literatureEarmuff and eye mask in the treatment of acute primary headache in emergency department: a randomized controlled open label study.PMC12664183Hassanien NTFSener AYıldırım CPamukcu Gunaydın GfalseEarmuff and eye mask in the treatment of acute primary headache in emergency department: a randomized controlled open label study.<h4>Background</h4>Patients presenting to the ED with headache are placed in a quiet, darkened room to minimize external stimuli; however, creating and maintaining such an environment can be challenging in the context of a busy ED setting. This study evaluated whether adding noise-reduction earmuffs and sleep eye masks to standard metoclopramide therapy improves pain relief in adult patients presenting with acute primary headache in the emergency department.<h4>Methods</h4>This single-center, open-label, randomized, controlled, parallel-group trial was conducted in the urban emergency department of a tertiary care hospital. Adult patients diagnosed with primary headache were randomized (1:1:1:1) to receive: Standard treatment alone (10 mg metoclopramide in 150 mL normal saline over 10 min)2025-01-01T00:00:00Z2025 Nov2026-06-05T21:40:37.622Z2026-05-22T03:16:03.245ZS-EPMC126641834131599610.1186/s12873-025-01405-7