biostudies-literatureUnknown26(1)Mohanta KM<h4>Background</h4>Plants are always exposed to a variety of stressful environments, including heat and drought stress, which severely impact the growth, development, and productivity of the plants. To overcome such challenges, plants have evolved diverse arrays of defense mechanisms. Among several defense strategies, the expression and evolution of heat stress-tolerant proteins are crucial. They protect the cellular structures, maintain cellular homeostasis, and overcome stress conditions. Although several studies have been conducted to identify the heat-and cold-stress-tolerant proteins, studies using the physicochemical properties of the proteins remain scarce. Therefore, we used melting temperature-based identification of heat and cold tolerant proteins in A. thaliana.<h4>Results</h4>TBMC genomics1082https://www.ebi.ac.uk/biostudies/studies/S-EPMC12664233biostudies-literatureMeltome Atlas of Arabidopsis thaliana proteome: a melting temperature-based identification of heat and cold resistant proteins using in-silico approach.PMC12664233Mohanta TKMohanta KMfalseMeltome Atlas of Arabidopsis thaliana proteome: a melting temperature-based identification of heat and cold resistant proteins using in-silico approach.<h4>Background</h4>Plants are always exposed to a variety of stressful environments, including heat and drought stress, which severely impact the growth, development, and productivity of the plants. To overcome such challenges, plants have evolved diverse arrays of defense mechanisms. Among several defense strategies, the expression and evolution of heat stress-tolerant proteins are crucial. They protect the cellular structures, maintain cellular homeostasis, and overcome stress conditions. Although several studies have been conducted to identify the heat-and cold-stress-tolerant proteins, studies using the physicochemical properties of the proteins remain scarce. Therefore, we used melting temperature-based identification of heat and cold tolerant proteins in A. thaliana.<h4>Results</h4>T2025-01-01T00:00:00Z2025 Nov2026-06-05T21:18:02.797Z2026-05-22T03:08:41.338ZS-EPMC126642334131043510.1186/s12864-025-12131-6